Objective: Pneumoperitoneum is the basic step in every laparoscopic procedure, and has been established in previous studies as a trigger for bacterial translocation. Toll-like receptor 4 (TLR-4) is responsible for the recognition of bacterial endotoxin or lipopolysaccharide (LPS) and for initiation of gram-negative bacillary septic shock syndrome. Our objective was to determine the effects of elevated intaabdominal pressure (IAP) on bacterial translocation and TLR-4 signaling in a rat model of a
Introduction: Persistently elevated plasma levels of proangiogenic proteins including VEGF, Angiopoietin 2 (Ang2) and Matrix Metalloproteinase 2 (MMP2) have been noted for 3-5 weeks after colorectal cancer (CRC) resection. Whereas increases early after surgery may be due to the brief acute inflammatory response, the origin of the week 2-5 elevations is uncertain. We hypothesize that wounds are a major source since angiogenesis plays a critical role in wound healing. This study’s purpose is to de
Introduction: The laparoscopic surgery has been evolved by development of the various laparoscopic surgical systems, for example, the robotic surgical system or the 3-dimension laparoscopic surgery system. In addition, the laparoscopic instrument such as forceps and energy devices has been progressing developed. As a result, the evaluation of their usability should be required. In general 3D camera system has believed to be better than 2D camera system, however there is no report of proving adva
Introduction: Long term outcome of endoscopic papillotomy was found to be relatively favorable, so cholecystectomy is not always necessary.That might be of clinical importance in selected groups, such as high operative risk patients and elderly.The aim of this study is to present the natural history of elderly patients after endoscopic papillotomy and to define the need for subsequent cholecystectomy.
Methods: A retrospective analysis of all patients above 60 years old, who underwent ERCP for b
Introduction: Recent studies in bariatric surgery have demonstrated a statistically significant dose-response association of increasing intravenous hydration (ml/kg/hr) progressively decreasing the incidence of extended hospital length of stay (eHLOS) (Fig. 1) [1]. However, attainment of a recommended ‘liberal’ intravenous fluid hydration strategy during these procedures with median surgical times of 1.0 [0.9-1.1] hrs is difficult [1]. A post-hoc analysis of the duration of nil per os (NPO) reve