The Efficacy of Laparoscopic Mini-Gastric Bypass for Type 2 Diabetes in Obese Patients: The Bezmialem Preliminary Report

Halil Coskun, MD, Suleyman Bozkurt, MD, Naim Memmi, MD, Gokhan Cipe, MD, Yeliz Emine Ersoy, MD, Oguzhan Karatepe, MD, Mustafa Hasbahceci, MD, Erhan Aysan, MD, Adem Akcakaya, MD, Mahmut Muslumanoglu, MD

Bezmialem Vakif University School of Medicine Department of Surgery, Istanbul Turkey

Background: Type 2 diabetes mellitus (T2DM) is a global health problem worldwide especially in obese population. The aim of this study is to evaluate the efficacy and safety of laparoscopic mini-gastric bypass in obese T2DM patients.

Material and Methods: Twenty-four consecutive patients with BMI >35 kg/m2 plus T2DM underwent LMGB at our hospital from January 2010 to January 2012. Preoperative T2DM related data including glycosylated hemoglobin (HbA1c), fasting and 2 h postprandial glucose, C-peptide levels were compared with data collected at 1, 3 and 6 postoperative months.

Results: Eighteen patients were female. Mean age was 39.9 years (range 27-58 years), mean preoperative BMI was 39.2 kg/m2 (range 35.3-48.7 kg/m2), and mean duration of T2DM was 5.4 years (range 2-11 years). Before LMGB 9 patients were taking oral antidiabetics and 15 were under insulin treatment. Mean operative time was 108 min (range 85-190 min) and mean hospital stay was 3.5 (range 3-5 days) days. Neither mortality nor major complications observed (only minor bleeding in 1 patient). Mean preoperative HbA1c, fasting and 2 h postprandial glucose, C-peptide level were 9.8% (range 7.3-13.1%), 254 mg/dl (range 145-310 mg/dl), 348 mg/dl (range 208-540 mg/dl) and 2.92 ng/ml (range 1.67-5.88 ng/dl) respectively. These data at 6 months after operation were 6.2% (range 5.3-8.6 %), 142 mg/dl (range 76-188 mg/dl), 190 mg/dl (100-248 mg/dl) and 2.14 ng/ml (0.35-3.08 ng/dl) respectively.

Conclusion: Although long-term follow-up data are required, early results of LMBG on T2DM patients were satisfactory and safe in terms of glycemic control.

Session: Poster Presentation

Program Number: P429

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