Background: Lipid management aimed at lowering LDL cholesterol, raising HDL cholesterol, and lowering triglycerides reduces macrovascular disease and mortality in patients with T2DM, particularly in those who had prior cardiovascular events. The objective of this study is to evaluate the control of dyslipidemia in patients with Type 2 Diabetes (T2DM) with BMI below 30 that were submitted to the laparoscopic ileal interposition associated to a sleeve gastrectomy (LII-SG).
Methods: The procedure was performed in 72 patients. 51 were men and 21 women. Mean age was 52.8 years (38-66). Mean BMI was 26.7 kg/m2 (22.1 – 29.4). All patients had the diagnosis of T2DM for at least 3 years and evidence of stable treatment with oral hypoglycemic agents and or insulin for at least 12 months. Insulin therapy was been used by 51.4 of the patients. Mean duration of T2DM was 10.5 years (3-22). Mean A1c was 8.5%. Hypercholesterolemia was diagnosed in 68% of the patients and Hypertriglyceridemia in 60.6%. LDL was abnormal in 68% of the patients and HDL in 34.7%. Mean NEFFA was 0.68mmol/l. Forty patients (55.5%) had arterial hypertension.
Results: Mean post-operative follow-up was 24.5 months (12-38). Mean postoperative BMI was 21.2.kg/m2 (17 – 26.7). Mean A1c was 6.1%, ranging 4.4 to 8.3. Overall, 91.4% of the patients achieved an adequate glycemic control (A1c < 7) without anti-diabetic medication. A1c below 6 was achieved by 50%, 41.4% had A1c between 6 and 7 and 8.6% had A1c above 7. Total hypercholesterolemia was normalized in 96.2% and Hypertriglyceridemia in 86.4% of the patients. LDL below 100 mg/dl was seen in 85.7% of the patients. Mean NEFFA decreased to 0.5mmol/l.
Conclusions: The LII-SG was an effective operation for the regression of dyslipidemia and T2DM in a non-obese (BM
Session: Podium Presentation
Program Number: S040