Pre-Operative Predictive Factors for Gallbladder Cholesterol Polyps Using Clinical Features

Chung-Yun Kim, PhD MD, Sung-Ock Suh, PhD MD, Young-Chul Kim, PhD MD, Wan-Bae Kim, PhD MD, Hyung-Joon Han, PhD MD, Tae-Jin Song, PhD MD, Sang-Yong Choi, PhD MD, Sae-Byeol Choi, PhD MD, Dong-Sik Kim, PhD MD. Korea University Anam Hospital

Background: This study was designed to determine the clinical data that might be useful for differentiating cholesterol gallbladder polyps from other benign or malignant gallbladder polyps by comparing clinical, laboratory parameters and radiologic findings, such as serum cholesterol and body mass index(BMI) with postoperative pathology findings.

Materials and Methods: Thirty-nine patients underwent laparoscopic cholecystectomy for a GB polyp without any combined cholecystitis during 2009 in Korea University Anam Hospital. They were divided into two groups, one with cholesterol polyps and the other with non-cholesterol polyps according to the pathologic diagnosis. Clinical features such as gender, age, BMI, size and number of polyps, the presence of a GB stone, the radiological measured maximum diameter and number of the polyp by US and CT scanning, and the serum total cholesterol, triglyceride, HDL and LDL levels were recorded for comparative analysis.

Results: Thirty of the thirty-nine cases were cholesterol polyps (76.9%) whereas other nine cases were adenomas (23.1%). The cholesterol polyp group had smaller size(less then 5mm), more multiple in nature(more then 3) and had higher BMI(above 25) with higher level of total cholesterol, triglyceride and LDL compared with non-cholesterol group. And above clinical features showed statistically significant differences in two groups (p<0.05).

Conclusions: In our study when if the GB polyp showed small size with multiplicity and if the patient is obese with high level of cholesterol, yearly follow-up is advisable because the GB polyp has higher chance of being cholesterol polyp.

Session: Poster
Program Number: P406
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