Muhammad Nadeem, MBBS1, John L Butsch, MD2, Steven D Schwaitzberg, MD1. 1University at Buffalo, 2Buffalo General Medical Center
Introduction: Mitochondria is a small energy producing structure of a cell. Mitochondrial myopathy (MM) is clinically mixed disorder which can affect various systems besides skeletal muscle. MM starts with muscle weakness or exercise weakness. This study is aimed to see effects of MM on gastrointestinal system likes gastroesophageal reflux disease (GERD) and gall bladder issues.
Methods: This was a retrospective chart review study using the quantitative data. Between May 2011 and June 2016, 124 patients who underwent muscle deep biopsy for confirming the MM at Buffalo General Hospital were included in this study. The data were analyzed using SPSS version 21.
Results: Out of 124(79% female, 21% male) mitochondrial myopathy patients, 40.3% and 21% patients were suffering from GERD and gall bladder issues respectively. 24.2% and 48.4% patients had obstructive sleep apnea (OSA) and fatigue respectively.
Conclusion: MM causes muscle weakness which results in affecting gastroesophageal system causing GERD and gall bladder issues. It causes OSA and fatigue as well.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 79846
Program Number: P386
Presentation Session: Poster (Non CME)
Presentation Type: Poster
