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Impact of patient age on morbidity and survival following laparoscopic pancreaticoduodenectomy

Lingwei Meng1, Qinghong Xia2, Yunqiang Cai1, Yongbin Li1, Bing Peng3. 1Department of General Surgery, ChengduShangjinNanfu Hospital, 2Department of Operation Room, ChengduShangjinNanfu Hospital, 3Department of Pancreatic Surgery, West China Hospital of Sichuan University

AIM: To present short- and long-term outcomes in elderly patients who performed laparoscopic pancreaticoduodenectomy (LPD) compared with the young.

METHODS: A total of 189 patients who performed LPD were enrolled in this study. The clinical data relating to these patients were collected in our hospital from October 2010 to September 2017. They were stratified according to age: young (<70 years), elderly (≥70 years).The postoperative morbidity, mortality and survival were analyzed.

RESULTS: Thirty-four elderly patients were included in the study. The comorbidities of hypertension and chronic anemia in elderly patients were higher than the young group ( p=0.005 and p<0.001). The intraoperative and postoperative information showed no significant differences between the young and the elderly groups. And there were no significant differences in terms of the rate and severity of short-term complications, pathological outcomes and other surgical outcomes between the two groups. Furthermore, the median overall survival times of pancreatic adenocarcinoma were 25 months in the young while 17 months in the elderly and the median overall survival times of periampullary adenocarcinoma were 46.3 months in the young while 30.6 months in the elderly. The median overall survival in two malignant diseases of the young patients was not significantly better than the elderly (p = 0.131 and p = 0.190).

CONCLUSION: Our data suggest that patient age showed little influence on postoperative morbidity, mortality and long-term survival in pancreatic adenocarcinoma and periampullary adenocarcinoma following LPD while studies with larger sample size and longer follow-up are necessary before definitive conclusions can be made.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 91039

Program Number: ETP833

Presentation Session: Emerging Technology iPoster Session (Non CME)

Presentation Type: Poster

46

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