• Skip to main content
  • Skip to header right navigation
  • Skip to site footer

Log in
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
www.sages.org

SAGES

Reimagining surgical care for a healthier world

  • Home
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Awards
    • Who Is SAGES?
    • Leadership
    • Our Mission
    • Advocacy
    • Committees
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Committee Rosters
      • SAGES Past Presidents
  • Meetings
    • SAGES NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2026 Scientific Session Call for Abstracts
      • 2026 Emerging Technology Call for Abstracts
    • CME Claim Form
    • SAGES Past, Present, Future, and Related Meeting Information
    • SAGES Related Meetings & Events Calendar
  • Join SAGES!
    • Membership Application
    • Membership Benefits
    • Membership Types
      • Requirements and Applications for Active Membership in SAGES
      • Requirements and Applications for Affiliate Membership in SAGES
      • Requirements and Applications for Associate Active Membership in SAGES
      • Requirements and Applications for Candidate Membership in SAGES
      • Requirements and Applications for International Membership in SAGES
      • Requirements for Medical Student Membership
    • Member Spotlight
    • Give the Gift of SAGES Membership
  • Patients
    • Join the SAGES Patient Partner Network (PPN)
    • Patient Information Brochures
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find A SAGES Surgeon
  • Publications
    • Sustainability in Surgical Practice
    • SAGES Stories Podcast
    • Patient Information Brochures
    • Patient Information From SAGES
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • MesSAGES – The SAGES Newsletter
    • COVID-19 Archive
    • Troubleshooting Guides
  • Education
    • Wellness Resources – You Are Not Alone
    • Avoid Opiates After Surgery
    • SAGES Subscription Catalog
    • SAGES TV: Home of SAGES Surgical Videos
    • The SAGES Safe Cholecystectomy Program
    • Masters Program
    • Resident and Fellow Opportunities
      • MIS Fellows Course
      • SAGES Robotics Residents and Fellows Courses
      • SAGES Free Resident Webinar Series
      • Fluorescence-Guided Surgery Course for Fellows
      • Fellows’ Career Development Course
    • SAGES S.M.A.R.T. Enhanced Recovery Program
    • SAGES @ Cine-Med Products
      • SAGES Top 21 Minimally Invasive Procedures Every Practicing Surgeon Should Know
      • SAGES Pearls Step-by-Step
      • SAGES Flexible Endoscopy 101
    • SAGES OR SAFETY Video Activity
  • Opportunities
    • Fellowship Recognition Opportunities
    • SAGES Advanced Flexible Endoscopy Area of Concentrated Training (ACT) SEAL
    • Multi-Society Foregut Fellowship Certification
    • Research Opportunities
    • FLS
    • FES
    • FUSE
    • Jobs Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • OWLS/FLS
You are here: Home / Abstracts / Fasting Insulin as a Surrogate Marker for Cardiac Risk in Patients Undergoing Bariatric Surgery

Fasting Insulin as a Surrogate Marker for Cardiac Risk in Patients Undergoing Bariatric Surgery

Zeenat Hasan, MD, Dan Eisenberg, MD

Stanford school of medicine and Palo Alto VA HCS

Introduction

The Framingham risk score has been shown to correlate with future risk of developing cardiovascular disease. Morbid obesity is known to increase the risk for cardiovascular disease, while bariatric surgery has been shown to decrease markers of cardiovascular risk. In this study we examined the correlation between changes in fasting insulin levels and the Framingham Risk score in pre- and post-operative bariatric surgery patients.

Methods
After IRB approval we performed a retrospective analysis of a prospective database of bariatric surgery patients at the Palo Alto VA Hospital. Data for age, gender, weight, laboratory values, and smoking history were obtained. Correlation between changes in fasting insulin levels and Framingham risk scores was determined using a Pearson correlation coefficient.

Results
Of 202 total patients who had bariatric surgery between 2005 and 2011, 48 were available for a minimum of one year follow up. Gastric bypass, sleeve gastrectomy, and adjustable gastric banding comprised 2.1%, 93.8%, and 4.2% of the operations, respectively. There were 39 males (81.3%) with a mean age of 53 years and a mean pre-operative body mass index of 46.4 kg/m2. Of these, 47.9% were taking diabetic medications at the time of surgery. The average mean excess body weight lost was 60%. All patients had a decrease in fasting insulin 1- year after surgery, with a mean decrease of 31.2 mU/L. The average preoperative fasting insulin level was 44.2 mU/L, and the average one year post operative fasting insulin level was 13.0 mU/L. There was a corresponding decrease in the Framingham risk score by -6.8%. The average preoperative Framingham risk score was 19.1%, and the average one year post operative Framingham risk score was 12.3%. The Pearson correlation coefficient was 0.3.

Conclusions
We found an average decrease in fasting insulin levels 1-year after bariatric surgery. Although both decreased, the fasting insulin level correlated, but weakly, with changes in the calculated Framingham risk score for cardiovascular disease. Fasting insulin levels can be used as an adjunct marker for cardiovascular risk.


Session: Poster Presentation

Program Number: P438

75

Share this:

  • Click to share on X (Opens in new window) X
  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on LinkedIn (Opens in new window) LinkedIn
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Mastodon (Opens in new window) Mastodon
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on Bluesky (Opens in new window) Bluesky

Related


sages_adbutler_leaderboard

Hours & Info

11300 West Olympic Blvd, Suite 600
Los Angeles, CA 90064

1-310-437-0544

[email protected]

Monday – Friday
8am to 5pm Pacific Time

Find Us Around the Web!

  • Bluesky
  • X
  • Instagram
  • Facebook
  • YouTube

Copyright © 2025 · SAGES · All Rights Reserved

Important Links

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals