• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

SAGES

Reimagining surgical care for a healthier world

  • Home
    • COVID-19 Annoucements
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Who is SAGES?
    • SAGES Mission Statement
    • Advocacy
    • Strategic Plan, 2020-2023
    • Committees
      • Request to Join a SAGES Committee
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Full Committee Rosters
      • SAGES Past Presidents
    • Donate to the SAGES Foundation
    • Awards
      • George Berci Award
      • Pioneer in Surgical Endoscopy
      • Excellence In Clinical Care
      • International Ambassador
      • IRCAD Visiting Fellowship
      • Social Justice and Health Equity
      • Excellence in Community Surgery
      • Distinguished Service
      • Early Career Researcher
      • Researcher in Training
      • Jeff Ponsky Master Educator
      • Excellence in Medical Leadership
      • Barbara Berci Memorial Award
      • Brandeis Scholarship
      • Advocacy Summit
      • RAFT Annual Meeting Abstract Contest and Awards
  • Meetings
    • NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2023 Scientific Session Call For Abstracts
      • 2023 Emerging Technology Call For Abstracts
    • CME Claim Form
    • Industry
      • Advertising Opportunities
      • Exhibit Opportunities
      • Sponsorship Opportunities
    • Future Meetings
    • Past Meetings
      • SAGES 2022
      • SAGES 2021
    • Related Meetings Calendar
  • Join SAGES!
    • Membership Benefits
    • Membership Applications
      • Active Membership
      • Affiliate Membership
      • Associate Active Membership
      • Candidate Membership
      • International Membership
      • Medical Student Membership
    • Member News
      • Member Spotlight
      • Give the Gift of SAGES Membership
  • Patients
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Patient Information Brochures
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find a SAGES Member
  • Publications
    • SAGES Stories Podcast
    • SAGES Clinical / Practice / Training Guidelines, Statements, and Standards of Practice
    • Patient Information Brochures
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • SCOPE – The SAGES Newsletter
    • COVID-19 Annoucements
    • Troubleshooting Guides
  • Education
    • OpiVoid.org
    • SAGES.TV Video Library
    • Safe Cholecystectomy Program
      • Safe Cholecystectomy Didactic Modules
    • Masters Program
      • SAGES Facebook Program Collaboratives
      • Acute Care Surgery
      • Bariatric
      • Biliary
      • Colorectal
      • Flexible Endoscopy (upper or lower)
      • Foregut
      • Hernia
      • Robotics
    • Educational Opportunities
    • HPB/Solid Organ Program
    • Courses for Residents
      • Advanced Courses
      • Basic Courses
    • Video Based Assessments (VBA)
    • Robotics Fellows Course
    • MIS Fellows Course
    • Facebook Livestreams
    • Free Webinars For Residents
    • SMART Enhanced Recovery Program
    • SAGES OR SAFETY Video
    • SAGES at Cine-Med
      • SAGES Top 21 MIS Procedures
      • SAGES Pearls
      • SAGES Flexible Endoscopy 101
      • SAGES Tips & Tricks of the Top 21
  • Opportunities
    • NEW-Area of Concentrated Training Seal (ACT)-Advanced Flexible Endoscopy-Coming Soon!
    • SAGES Fellowship Certification for Advanced GI MIS and Comprehensive Flexible Endoscopy
    • Multi-Society Foregut Fellowship Certification
    • SAGES Research Opportunities
    • Fundamentals of Laparoscopic Surgery
    • Fundamentals of Endoscopic Surgery
    • Fundamental Use of Surgical Energy
    • Job Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
  • Store
    • “Unofficial” Logo Products
  • Log In

Efficacy of laparoscopic anti-reflux surgery for non-erosive gastroesophageal reflux disease assessed by combined multichannel intraluminal impedance-pH monitoring

Fumiaki Yano, Nobuo Omura, Kazuto Tsuboi, Masato Hoshino, Se Ryung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Koji Nakada, Katsunori Nishikawa, Norio Mitsumori, Hideyuki Kashiwagi, Katsuhiko Yanaga. Department of Surgery, The Jikei University School of Medicine

INTRODUCTION: Due to the high prevalence of PPI resistance, treatment of non-erosive gastroesophageal reflux disease (NERD) is challenging as compared to gastroesophageal reflux disease with reflux esophagitis (GERD). The aim of this study was to investigate the therapeutic effects of laparoscopic anti-reflux surgery (LARS) for NERD using 24-h combined multichannel intraluminal impedance-pH monitoring (MII-pH).

METHODS AND PROCEDURES: Between February 2009 and August 2015, 30 patients (mean age, 48.5 years, 11 women) who underwent LARS for NERD underwent MII-pH monitoring before and at 3 months after surgery. Reflux events were classified by pH as acid or non-acid reflux. Intraesophageal pH<4 holding time (pH<4), longest episode, episodes over 5 min, DeMeester score, and the numbers of acid and non-acid reflux episodes were calculated with the patient in both liquid and gas reflux. The symptom index (SI) and symptom association probability (SAP) were also evaluated.

RESULTS: Twenty-six patients (87%) had hiatal hernia. The results of reflux events were listed on the table. The liquid pooling in the esophagus after surgery was possibly detected as non-acid gastroesophageal reflux. Both SI and SAP improved significantly after surgery (p=0.011, 0.005).

CONCLUSIONS: 1) LARS for NERD completely controlled all acid reflux events and patients’ symptoms. 2) As unidentified complaints after surgery, liquid pooling in the esophagus could be detected as non-acid gastroesophageal reflux.

 

Table

  pH<4HT

LE

> 5 min

DM

LAR

LNAR

GAR

GNAR

TR

pre

3.8±4.9

11.5±15.1

2.0±3.0

13.5±15.9

32.6±25.9

34.4±27.2

3.8±8.2

15.6±17.8

83.2±51.2

post

0.5±1.1

1.8±3.7 0.2±0.7

2.4±4.0

8.3±14.9 27.1±25.6 0.8±1.2 12.5±11.2 48.4±38.2

p-value

<0.001

<0.001

0.004

<0.001

<0.001

0.121 0.04 0.445 <0.001

                                                                                                     mean±S.D.

pH<4HT; pH<4 holding time (%), LT; Longest episode (min), > 5 min; episode over 5 min., DM; DeMeester score, LAR/LNAR; Liquid acid reflux/non-acid reflux,GAR/GNAR; Gas acid reflux/non-acid reflux, TR; Total reflux

92

Share this:

  • Twitter
  • Facebook
  • LinkedIn
  • Pinterest
  • WhatsApp
  • Reddit

Related

« Return to SAGES 2016 abstract archive

Our Mission

Innovate, educate and collaborate to improve patient care.

Recently, on SAGES…

Critical View of Safety (CVS) Challenge QR Code

The SAGES Critical View of Safety Challenge – Donate Your Lap Chole Videos!

The Society of American Gastrointestinal and Endoscopic Surgeons is hosting the first Artificial Intelligence Data Challenge conducted by surgeons. The aim of this challenge is to generate a large and diverse dataset of laparoscopic cholecystectomy videos, annotated with respect to the subcomponents of the Critical View of Safety (CVS). Computer scientists from all over the […]

Respuesta de SAGES al Estudio NordICC sobre el beneficio de las colonoscopias de detección

SAGES desea aclarar los resultados del estudio NordICC y colocarlos en contexto de los esfuerzos de varias agencias nacionales para reducir el riesgo de cáncer colorrectal – la segunda causa de muerte por cáncer más frecuente en los Estados Unidos-, mediante la promoción de la detección y tratamiento oportuno de las lesiones.

SAGES Response to NordICC Study Regarding Benefit of Screening Colonoscopies

The NordICC Study recently published in The New England Journal of Medicine and widely reported on by media outlets has raised questions regarding the benefit of screening colonoscopy in lowering the risk of colorectal cancer and cancer-related deaths among otherwise healthy and symptom-free men and women aged 55 to 64. Provocative headlines and commentaries have […]

Contact SAGES

Society of American Gastrointestinal and Endoscopic Surgeons
11300 W. Olympic Blvd Suite 600
Los Angeles, CA 90064 USA
webmaster@sages.org
Tel: (310) 437-0544

Find Us Around the Web!

  • Facebook
  • Twitter
  • YouTube

Important Links

SAGES 2023 Meeting Information

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals

 

  • taTME Study Info
  • Foundation
  • SAGES.TV
  • MyCME
  • Educational Activities

Copyright © 2023 Society of American Gastrointestinal and Endoscopic Surgeons