Maximizing Coupling Strength of Magnetically Anchored NOTES Instruments: How Thick Can We Go?
Introduction: The Magnetic Anchoring and Guidance System (MAGS) includes a handheld external magnet that controls deployable internal surgical instruments (camera, auxiliary light source, grasper, retractors, and cautery dissector) via magnetic attraction forces. We have successfully performed transvaginal NOTES cholecystectomy using MAGS instruments in porcine models with up to 2.5cm thick abdominal walls. The purpose of… Continue Reading
- Type:
- Posters
- Topic:
- Endolumenal / NOTES
Maximizing the donor pool: Use of right kidneys and multiple arteries for live donor kidney transplantation
Introduction: The first laparoscopic donor nephrectomy (LDN) was performed in 1996. Since that time, LDN is becoming standard of care for organ procurement. Donor and recipient outcomes have been proven equivocal for laparoscopic and open nephrectomy. In the past, LDN was avoided when procuring the right kidney or organs with multiple arteries. Reviewing our experience… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Solid Organ and Endocrine
Mechanisms of Ventral Hernia Recurrence Following Laparoscopic Repair
Objective: To determine mechanisms of ventral hernia recurrence following laparoscopic repair.Background: Laparoscopic ventral hernia repair techniques have demonstrated low recurrence rates in recent years. Mechanisms of recurrence following open repair are well-documented, but there is less data defining how laparoscopically-repaired hernias recur.Methods: We performed a retrospective analysis of 25 patients who had previously undergone at… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Abdominal Wall Hernias
Mesenteric Defect Closure and Prevention of Internal Herniation Following Laparoscopic Roux-en-Y Gastric Bypass
Background: Internal herniation is a dangerous complication following laparoscopic roux-en-y gastric bypass (LRYGB). Available studies have shown no clear benefit to operative closure of the jejunal mesenteric defect at the time of LRYGB.Objective: To analyze the impact of mesenteric defect closure on the incidence of internal herniation following LRYGB.Methods: We performed a retrospective study of… Continue Reading
- Type:
- Posters
- Topic:
- Metabolic / Obesity
Mesh Complications after Prosthetic Reinforcement of Hiatal Closure. A 29 Case Series.
Background:Primary laparoscopic hiatal hernia repair is associated with up to a 42% recurrence rate. This has lead to the use of mesh for crural repair, which has resulted in an improved recurrence rate (0-24%). However, mesh complications have been reported. Methods:We compiled three cases and our senior author contacted other experienced esophageal surgeons who provided… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Outcomes and Quality
Microbial Contamination of the Peritoneum Is Common Following Transgastric Endoscopic Surgery
INTRODUCTION: In Natural Orifice Transluminal Endoscopic Surgery (NOTES), intentional perforation of viscus to access the peritoneal cavity violates basic principles of surgery and raises questions regarding its safety. The aim of this study was to investigate if the transgastric approach could affect the peritoneal cavity by transluminal contamination. MATERIALS AND METHODS: A total of 7… Continue Reading
- Type:
- Posters
- Topic:
- Endolumenal / NOTES
Minimal Hospital Stay and Morbidity in the Laparoscopic Treatment of Distal Pancreatic Lesions
Background: There is an increasing trend towards treating distal pancreatic lesions with minimally invasive surgical techniques in order to facilitate both a quicker recovery and fewer complications. Most studies to date have shown a median hospital stay of four to five days. Our data reveal that distal pancreatic cystic and solid tumors can be removed… Continue Reading
- Type:
- Posters
- Topic:
- Solid Organ and Endocrine
Minimal Thermal Effects of a Continuous Power Delivery System with Bipolar Sealing Capability As Measured By High Definition Thermography
Objective of the study: Evaluate the real time thermal footprint of a continuous power delivery technique with bipolar sealing technology as measured by high-definition thermography. Description of the methods: Thermography is the use of an infrared imaging camera to record the radiating heat in real time, as thermal energy is emitted from an object. In… Continue Reading
- Type:
- Posters
Minimally invasive colon resection is associated with increased sVEGFR1 and decreased sVEGFR2 plasma levels early after surgery; the net impact is decreased binding of free VEGF which may account for increased plasma VEGF levels early post surgery
Introduction: Plasma VEGF levels are increased after minimally invasive colorectal resection (MICR) for both benign and malignant disease. VEGF, which is critical to both wound healing and tumor growth, induces angiogenesis by binding to endothelial cell bound VEGF-Receptor 1 (VEGFR1) and VEGF-Receptor 2 (VEGFR2). Soluble VEGF-Receptor-1 (sVEGFR1) and soluble VEGF-Receptor-2 (sVEGFR2), which are not capable… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Colorectal
Minimally invasive colorectal resection for cancer but not benign disease is associated with a short lived decrease in soluble Tie-2 Receptor levels which likely promotes VEGF-mediated angiogenesis
Introduction: Plasma VEGF levels are increased after minimally invasive colorectal resection (MICR) and likely stimulate angiogenesis in the wound and in residual tumor deposits. Angiopoetin (Ang) 1, via binding to endothelial cell (EC) bound Tie-2 receptor (Tie2) inhibits VEGF mediated angiogenesis while Ang 2 encourages VEGF-related angiogenesis by preventing Ang-1’s effects via competitive binding of… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally invasive colorectal resection for malignant disease is associated with an early decrease in TGF Beta plasma levels one day postop and then an increase in levels in the second week after surgery
Introduction: TGF Beta regulates cell growth and proliferation. Although pro-apoptotic in general, in some cancers it promotes tumor angiogenesis via inactivation of the TGF signaling pathway. Some cancers express TGF Beta and it has been reported that elevated blood levels pre-resection are associated with advanced stage disease. Surgery’s impact on TGF Beta levels is unknown.… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally invasive colorectal resection is associated with a temporary decrease in FGF-2 levels in both cancer and benign indication patients.
Introduction: Fibroblast growth factor-2 (FGF-2) is a promoter of endothelial cell growth and angiogenesis and, thus, plays a role in both wound healing and tumor growth. Elevated blood levels have been reported in cancer (CRC) patients prior to colorectal resection (CR) and some investigators have noted decreased levels 1 month postop. Surgery’s early impact on… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally Invasive Ivor Lewis Esophagectomy
This video illustrates the preferred technique for minimally invasive esophagectomy at the University of Pittsburgh. Previously, our described technique included mobilization of the esophagus via thoracoscopy, laparoscopic creation of the gastric tube and construction of a cervical esophagogastric anastomosis. Although we have reported excellent outcomes with this technique, we have since modified the procedure to… Continue Reading
- Topic:
- Esophageal / Gastric Surgery
Minimally Invasive Ivor-Lewis Esophagogastrectomy for Gastric Cardia Cancer
Introduction: Gastric cardia cancer with involvement of the esophagus may require an esophagogastrectomy to obtain negative tumor margins. We have shown that minimally invasive esophagectomy is a safe approach for the treatment of esophageal cancer. We describe the technique of a minimally invasive Ivor Lewis esophagectomy in a patient with a large gastric cardia tumor.Methods:… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Esophageal / Gastric Surgery
Minimally Invasive Resection Techniques for Gastroesophageal Junction Gist Tumors
Introduction: Gastrointestinal Stromal Tumors (GIST) are relatively rare neoplasms of mesenchymal origin with uncertain malignant potential. Complete gross resection without a need for microscopically negative margins or lymph nodes is oncologically adequate. Minimally invasive resection techniques such as laparoscopic wedge gastectomy are feasible and safe. Unfortunately, GIST lesions located near the gastroesophageal junction can be… Continue Reading
- Topic:
- Esophageal / Gastric Surgery