Quality assessment after neoadjuvant therapy and TME


Presented by Mariana Berho, MD at the SAGES 2013 Annual Meeting; SAGES/ISLCRS/ASCRS Symposium – Optimizing Outcomes in Rectal Cancer

TNM stage–34 sec
neoadjuvant CRT–1:05
tumor downstaging vs tumor regression–1:54
importance of pTN after neoadjuvant CRT–3:25
citations–4:37 http://www.ncbi.nlm.nih.gov/pubmed/19673001

Keyword(s): ACS, American Journal of Surgery, anatomic study of distribution, anatomical LN mapping, Annals of Surgery, Archives of Surgery, ASCRS, autopsy study, biologic predictor, bowel tract, bowel wall, chemotherapy regimens, circumferential resection margins, circumferential margin, clinical outcome, clinical significance, clinical TN, College of American Pathologists, Colorectal Disease, comparative analysis, controversial results, coronal sections, cpN, CRT, curative surgery, current guidelines, DCR, death, disease free survival, disease stage, distant metastasis, Dutch TME trial, Dworak tumor regression grade system, endpoints, European Journal of Surgical Oncology, extramural vascular invasion, fat clearance LN harvest, feasibility, fibrosis, fibrotic changes, fibrotic tissue, gross exam, harvest, heterogeneity, high-dose chemoradiation, histological identification, histopathological study, histopathology, homogenious studies, immunohistochemical stains, immunological response, ink, International Journal of Surgical Pathology, interobserver variability, intraobserver variability, invasive rectal adenocarcinoma, ISLCRS, Journal of Clinical Oncology, Journal of Clinical Pathology, Kappa grade, Kappa level of agreement, Korea, Lancet, Lancet Oncology, lateral tumour spread, LN distribution, LN exam, LN harvesting, LN metastasis, LN mets, LN status, local recurrence, long-term outcomes, lymphovascular invasion, malignant cells, Mandard TRG system, mesorectal adipose tissue, mesorectal LNs, mesorectal plane, mesorectum, modern tx, modified fat clearing technique, molecular markers, MRC, muscularis propria plane, NCIC-CTG, nCRT, neoadjuvant therapy, node-negative, operable rectal cx, pathologic nodal status, pathological predictors, pathological prognostic factors, pathological response, pathological TN, pathologist, pCR, perirectal adipose tissue, plane of surgery, postop staging, postop tx, predictive factors, preop clinical stages, preop tx modalities, prognosis, prognosis predictor, prognostic implicator, prognostic significance, prognostic value, prospective randomized trial, pTN, pTN downstaging, quality assessment, radical surgery, radiotherapy, rate of differentiation, rectal cx, rectal cx specimen, rectal cx surgery, rectal wall, rectum, reproducibility, resection, residual tumor, scar, specimen, surgical excision, surgical resection, surgical specimen evaluation, survival, T classification, T stage, T0, three point grade systems, TME, TN staging system, TNM stage, toxicity, tumor differentiation, tumor effacement, tumor regression, tumor regression stage systems, tumor response, tumor volume, tumors, tumour regression, tumour regression grade, tx modalities, ulceration, undifferentiated cells, vascularization, vasculopathy, yPN, ypN0, ypT, ypT0-2 rectal cx, ypTN

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