• Skip to main content
  • Skip to header right navigation
  • Skip to site footer

Log in
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
www.sages.org

SAGES

Reimagining surgical care for a healthier world

  • Home
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Awards
    • Who Is SAGES?
    • Leadership
    • Our Mission
    • Advocacy
    • Committees
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Committee Rosters
      • SAGES Past Presidents
  • Meetings
    • SAGES NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2026 Scientific Session Call for Abstracts
      • 2026 Emerging Technology Call for Abstracts
    • CME Claim Form
    • SAGES Past, Present, Future, and Related Meeting Information
    • SAGES Related Meetings & Events Calendar
  • Join SAGES!
    • Membership Application
    • Membership Benefits
    • Membership Types
      • Requirements and Applications for Active Membership in SAGES
      • Requirements and Applications for Affiliate Membership in SAGES
      • Requirements and Applications for Associate Active Membership in SAGES
      • Requirements and Applications for Candidate Membership in SAGES
      • Requirements and Applications for International Membership in SAGES
      • Requirements for Medical Student Membership
    • Member Spotlight
    • Give the Gift of SAGES Membership
  • Patients
    • Join the SAGES Patient Partner Network (PPN)
    • Patient Information Brochures
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find A SAGES Surgeon
  • Publications
    • Sustainability in Surgical Practice
    • SAGES Stories Podcast
    • Patient Information Brochures
    • Patient Information From SAGES
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • MesSAGES – The SAGES Newsletter
    • COVID-19 Archive
    • Troubleshooting Guides
  • Education
    • Wellness Resources – You Are Not Alone
    • Avoid Opiates After Surgery
    • SAGES Subscription Catalog
    • SAGES TV: Home of SAGES Surgical Videos
    • The SAGES Safe Cholecystectomy Program
    • Masters Program
    • Resident and Fellow Opportunities
      • MIS Fellows Course
      • SAGES Robotics Residents and Fellows Courses
      • SAGES Free Resident Webinar Series
      • Fluorescence-Guided Surgery Course for Fellows
      • Fellows’ Career Development Course
    • SAGES S.M.A.R.T. Enhanced Recovery Program
    • SAGES @ Cine-Med Products
      • SAGES Top 21 Minimally Invasive Procedures Every Practicing Surgeon Should Know
      • SAGES Pearls Step-by-Step
      • SAGES Flexible Endoscopy 101
    • SAGES OR SAFETY Video Activity
  • Opportunities
    • Fellowship Recognition Opportunities
    • SAGES Advanced Flexible Endoscopy Area of Concentrated Training (ACT) SEAL
    • Multi-Society Foregut Fellowship Certification
    • Research Opportunities
    • FLS
    • FES
    • FUSE
    • Jobs Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • OWLS/FLS
You are here: Home / Abstracts / Single Anastomosis (Mini) Gastric Bypass versus Sleeve Gastrectomy: Meta-analysis of Randomized Clinical Trials

Single Anastomosis (Mini) Gastric Bypass versus Sleeve Gastrectomy: Meta-analysis of Randomized Clinical Trials

Zhamak Khorgami1, Saeed Shoar, MD2, Philip R Schauer, MD2, Stacy A Brethauer, MD2, Ali Aminain, MD2. 1University of Oklahoma, College of Medicine, Tulsa, OK, 2Bariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, Cleveland, OH

Introduction: While sleeve gastrectomy (SG) is the most common bariatric procedure worldwide, single anastomosis (mini) gastric bypass (SAGB) is rapidly gaining acceptance. As mid- to long-term effects of SAGB on weight and obesity-related comorbidities become available, a systematic review of the literature to summarize the available high quality data is required to direct future investigations and clinical practice.

Methods: A systematic literature review was conducted in PubMed/Medline and Cochrane Database through September 2018 to identify RCTs which compared weight loss outcome, diabetes mellitus (DM) and hypertension (HTN) remission, and postoperative complications between SAGB and SG.

Results: 3 RCTs encompassing 595 patients (297 SAGB patients and 298 LSG patients) were eligible to be enrolled into this meta-analysis. The longest follow-up was 5 years for 2 RCTs and 3 years for 1 RCT. Weight loss outcome was pooled based on percentage of total weight loss in 2 studies (significant in favor of SAGB) and percent excess weight loss in 2 studies (not significantly different). Moreover, while SAGB had a mild superiority in DM remission (effect size = 0.16, p = 0.02), the difference was not significant for HTN resolution (effect size = 0.17, p = 0.06). Postoperative adverse events were comparable between the 2 procedures (odds ratio = 0.80, p = 0.42).

Conclusion: Findings of this meta-analysis suggest that SAGB is associated with more weight loss compared with SG. Furthermore, while SG has remarkable effects on DM and HTN, SAGB is associated with about 15% higher chance of remission for both comorbidities. Both procedures are comparably safe.

Figure. Comparison of weight loss outcome (above: %weight loss and % excess weight loss), resolution of comorbid diabetes mellitus and hypertension (middle), and postoperative adverse events (below)


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 96053

Program Number: P072

Presentation Session: Poster Session (Non CME)

Presentation Type: Poster

View this Poster

54

Share this:

  • Click to share on X (Opens in new window) X
  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on LinkedIn (Opens in new window) LinkedIn
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Mastodon (Opens in new window) Mastodon
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on Bluesky (Opens in new window) Bluesky

Related


sages_adbutler_leaderboard

Hours & Info

11300 West Olympic Blvd, Suite 600
Los Angeles, CA 90064

1-310-437-0544

[email protected]

Monday – Friday
8am to 5pm Pacific Time

Find Us Around the Web!

  • Bluesky
  • X
  • Instagram
  • Facebook
  • YouTube

Copyright © 2025 · SAGES · All Rights Reserved

Important Links

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals