Caleb J Ba Mendoza1, Aisha Tabba1, Osamuyi Idubor1, Joel Miller1, Aliu Sanni, MD, FACS2. 1Philadelphia College of Osteopathic Medicine, 2Eastside Bariatric and General Surgery LLC
Introduction: Morbid obesity is associated with increased mortality secondary to cardiovascular risk factors including diabetes, hypertension and dyslipidemia. The most effective intervention for morbid obesity and associated risk factors is bariatric surgery. The aim of this study is to evaluate changes in lipid profiles following Laparoscopic Gastric Sleeve (LSG) or Laparoscopic Roux-en-Y Gastric Bypass (LRYGBP) one year after surgery.
Methods and Procedures: A systematic review of studies between 2005 and 2017 was conducted through Pubmed to identify studies with comparative data on lipid levels between Sleeve Gastrectomy and Roux-en-Y Gastric bypass postoperatively at 1 year. Outcomes analyzed were total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and BMI. The results are expressed as standard difference in means with standard error. Statistical analysis was done using fixed-effects meta-analysis to compare the mean value of the two groups. (Comprehensive Meta-Analysis Version 3.3.070 software; Biostat Inc., Englewood, NJ).
Results: Four out of 101 studies were quantitatively assessed and included in this meta-analysis. Among the studies, 1405 patients underwent Laparoscopic Roux-en-Y Gastric Bypass and 198 patients underwent Laparoscopic Sleeve Gastrectomy. There was significantly lower cholesterol (-0.667 ± 0.102; p<0.05) and LDL levels (-0.714± 0.103, p<0.05) for those patients who underwent LRGYBP as compared to LSG. HDL levels (-0.107 ± 0.001, p= 0.287), Triglyceride levels (-0.149±0.101, p=0.140), and BMI (0.119± 0.163, p=0.463) at 12 months postoperatively were similar in both groups.
Conclusion: Lipid profiles are significantly reduced following LRYGBP when compared to LSG in bariatric patients.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 93615
Program Number: P077
Presentation Session: Poster Session (Non CME)
Presentation Type: Poster
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