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You are here: Home / Abstracts / Hypertension Resolution After Rapid Weight Loss: A Single Institution Experience.

Hypertension Resolution After Rapid Weight Loss: A Single Institution Experience.

Cristian Milla Matute, MD, Camila Fonseca Mora, MD, David Gutierrez Blanco, Emanuele Lo Menzo, MD, PhD, FACS, Rama Ganga, MD, Samuel Szomstein, MD, FACS, Raul J Rosenthal. Cleveland Clinic Florida

INTRODUCTION: It is well known that morbid obesity is strongly associated with high blood pressure. Cardiovascular risk reduction is a well studied and described result of bariatric surgery. The objective of this study is to quantify hypertension resolution in patients who underwent bariatric surgery at our institution.

METHODS: We retrospectively reviewed all the patients who underwent either laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux en Y gastric bypass (LRYGB) at our institution between 2010 and 2015. We selected those patients who were on antihypertensive medical treatment and had a 12-month follow-up. Hypertension resolution was defined as the interruption of any blood pressure medications within the follow-up period. We compared the patients who had resolution of hypertension (group 1) with patients who did not (group 2), based on demographics, comorbidities, and outcomes. Chi-square and student T-test were used for categorical and continuous variables respectively.

RESULTS: Out of 1330 patients, 185 (13.9%) patients met the inclusion criteria, out of which, 73 (39.5%) had a complete resolution of hypertension within 12 months. The patient population included in Group 1 was predominantly female n=114 patients (61.8%), diabetic (n=87, 47%), with a mean BMI of 30.31±4.45 kg/m2, a mean age of 52.6±10.7 years, and a preoperative systolic blood pressure mean of 131±14.31 mmHg. The most common procedure performed was LSG with n=105 (57%).

Comparison between group 1 and group 2 based on age, gender, BMI, and diabetes showed no statistically significant difference.  Estimated BMI loss % at 12 months, type of procedure and %EBMIL showed no statistically significant difference between the groups.

CONCLUSIONS: Rapid weight loss is associated with a drastic reduction of blood pressure. Besides weight loss, we did not identify a clear correlation between risk factors when we compared patients who had resolution of hypertension with patients without resolution. Further prospective studies should be done for better understand these findings.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 87076

Program Number: P590

Presentation Session: iPoster Session (Non CME)

Presentation Type: Poster

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