Ziming Cui, Xiaoyu Dong, Weisheng Chen, Dexin Chen, Wei Jiang, Kai Li, Jun Yan. Department of General Surgery, Nanfang Hospital, Southern Medical University
BACKGROUND: There is still no consensus on the treatment of synchronous multiple primary colorectal cancers (CRCs). In this study, we aimed to compare the efficacy and safety of laparoscopic-assisted versus traditional open surgery for multiple primary CRCs.
METHODS: Between March 2006 and March 2018, 115 patients who suffered from synchronous multiple primary CRC with clinical stage among T1-4N0-2M0 were included. Efficacy and safety of laparoscopic-assisted group (n=75) and traditional open group (n=40) were compared. All patients were followed up every 6 months and were recorded the survival.
RESULTS: Two patients were converted to open surgery in the laparoscopic-assisted group. Both length of total and postoperative hospital stay were significantly shorter in the laparoscopic-assisted group than the traditional open group (median 16 vs 19 days, p = 0.004; median 10 vs 12 days, p = 0.006, respectively). The laparoscopic-assisted group yielded less blood loss (median 100 vs 125 mL, p = 0.003), shorter postoperative exhaust time but longer operation time (median 230 vs 197 mins, p = 0.031) than the traditional open group. There was no significant difference on the overall survival and disease-free survival between two groups.
CONCLUSION: Our results suggested that laparoscopic-assisted surgery is a more efficacious, relatively safer and minimally invasive treatment for synchronous multiple primary CRCs. Further randomized controlled trials with larger sample sizes are needed to strengthen the conclusion of this study.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 95120
Program Number: P295
Presentation Session: Poster Session (Non CME)
Presentation Type: Poster
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