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Can Bariatric Surgery Prevent the Development of Metabolic Syndrome?

Salman Alsabah, MBBS, MBA, FRCSC1, Eliana Al Haddad2, Aliaa Al-Mutawa1, Mohammad Al-Mutawa1, Jonathon D Vaz1. 1Kuwait University, 2Columbia University Medical Center

Introduction: Obesity has been directly correlated with the development of metabolic syndrome, a life-threatening disorder. With the constant rise of obesity in the world, this correlation has become of major significance.

Methods: A retrospective analysis of LSG patients’ medical records was performed between October 2008-2017 at a single institute in Kuwait. 1818 patients that have not been previously diagnosed as diabetic and/or dyslipidemic were included.

Results: Patients were followed-up for a 5-year period. Pre-operative weight and body mass index(BMI) were 123.8Kg and 46.1Kg/m2. The greatest weight loss was achieved at 1.5years post-operatively, correlating to a %excess weight-loss(EWL) of 73.8% and change in BMI of 14.62Kg/m2. Pre-operatively, only 45.1% of the patients exhibited normal FBS levels. This number dropped significantly throughout the follow-up period, corresponding to a normal FBS level in 77.8% at 12 months post-op. Only 20% of the patients had normal HbA1c levels pre-operatively, and this number increased to a maximum of 50.4% at 1-year. When it came to looking at the effect of LSG on lipid status, it was seen that it had little effect on total cholesterol and LDL levels, while our patients demonstrated significantly favorable results on HDL, VLDL and TG numbers

Conclusion: Our study was able to prove substantial positive results with regards to metabolic syndrome post-LSG, with a significant improvement in the glycemic and lipid profile of patients from numbers that are considered dangerous, to those that are in the normal range post-operatively. This improvement is not just due to the weight loss associated with the surgery, but also due to the nature of this procedure.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 92146

Program Number: P060

Presentation Session: Poster Session (Non CME)

Presentation Type: Poster

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