Authors: Joseph Talbet MD, David Pechman MD
Advanced Medical Solutions (Winsford, U.K.) received FDA approval for both the LIQUIFIX™ Precision Open Hernia Mesh Fixation (HMF) Device and LIQUIFIX FIX8® HMF Device on June 2, 2023.
The LIQUIFIX™ Precision Open HMF Device is intended for the use in open surgical repair of inguinal and ventral hernias; the LIQUIFIX FIX8® HMF Device is intended for use in laparoscopic repair of inguinal and ventral hernias. Each device allows for fixation of mesh against the abdominal wall or approximation of peritoneum against the abdominal wall.
Inguinal hernia repair is the most common surgical procedure done in the United States. Hernia repair with mesh requires fixation of the mesh to decrease the risk of recurrence and to increase the tensile strength. Mesh fixation methods include penetrating methods like tacks or self-fixating mesh. The latter decreases the risk of recurrence and is associated with increased operative time. Fibrin glue is another non-penetrating fixation method that is considered safe and associated with decreased post-operative pain, however, it cannot be used for peritoneal closure. N-2-butyl cyanoacrylate glue can be used for mesh fixation and peritoneal closure.
The LIQUIFIX™ Precision Open Hernia Mesh Fixation (HMF) Device is used to perform non-penetrating fixation during open procedures. The LIQUIFIX FIX8® HMF Device is used to perform non-penetrating fixation during laparoscopic procedures. It has a 5 mm diameter rigid delivery system with a trigger action. The trigger fires a 12.5 mg aliquot of anchor solution (100% n-butyl-2-cy-anoacrylate) and has 44 shots. Once fired the solutions require 5-10 seconds to set.
The in-use lifetime of the implanted adhesive is approximately 2 weeks. It provides temporarily hold to the mesh until it is integrated with the surrounding structures. The adhesive does not need to be removed.
Contraindications for the use of the device include but not limited to: 1) Patients with hypersensitivity to cyanoacrylate or formaldehyde. 2) Use of PTFE or absorbable mesh.3) Not to be used across mucocutaneous junctions or on skin that is regularly exposed to bodily fluids.
- A novel glue device for fixation of mesh and peritoneal closure during laparoscopic inguinal hernia repair: short and medium-term results; Dauser B, Szyszkowitz A, Seitinger G, Fortelny RH, Herbst F. 2016
2. TAPP surgery with mesh fixation and peritoneal closure using n-butyl-2-cyanoacrylate (LiquiBand FIX8®)—initial experience; Mittermair R, Jenic G, Kolenik R, Sorre C. 2015.