Two-year Outcomes of Randomized Controlled Trial Comparing Laparoscopic Greater Curvature Plication Versus Laparoscopic Sleeve Gastrectomy

V.v. Grubnik, Prof1, O.b. Ospanov, Prof2, K.a. Namaeva2, V.p. Golliak1, M.s. Kresun1. 1Odessa national medical university, Ukraine, 2Medical university Astana, Kazakhstan

Introduction. Laparoscopic greater curvature placation (LGCP) is a new restrictive bariatric procedure witch has a similar restrictive mechanism like laparoscopic sleeve gastrectomy (LSG) without potential risk of leak.

Aim of the study was to compare 2-years results of LSG and LGCP.

Methods and procedures. Multicenter prospective randomized study was started in 2010. A total 52 patients with morbid obesity were allocated either to LGCP group (n=25) or LSG group (n=27). Main exclusion criteria were: ASA > III, age > 75, BMI>65 kg/m2. There were 40 women and 12 men, mean age was 42,6±6,8 years (range, 35-62). Data on the operation time, complications, hospital stay, body mass index loss (BMIL), percentage of excess weight loss (%EWL), loss of appetite and improvement of comorbidities were collected during the follow-up examination.

Results. All procedures were completed laparoscopically. The mean operative time was 92,0±15 min for LSG and 73±19 min for LGCP (p>0,05). The mean hospital stay was 4,0±1,9 days in the LSG group and 3,8±1,7 days in LGCP group (p>0,05). One year after surgery, the mean %EWL was 59,5±15,4% in LSG group and 45,8±17% in LGCP group (p>0,05). After 2 years, mean %EWL was 78,9%±20% in the LSG group and 42,4±18% in the LGCP group (p<0,01). Loss of feeling of hunger was 28% in LGCP group and 76% in the LSG group (p<0,05). The comorbidities including diabetes, sleep apnea and hypertension, were markedly improved in both group after surgery.

Conclusions. The short-term outcomes of the study demonstrate the equal effectiveness of both procedure, but 2-years follow-up showed that LGCP is worse than LSG as a restrictive procedure for weight loss.

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