The validity for the laparoscopic colorectal surgery using the absorbable adhesion barrier made of oxidized regenerated cellulose

Masanori Naito, MD, PhD, Masahiko Watanabe, MD, PhD, Ken Kojo, MD, Takahiro Yamanashi, MD, PhD, Naoto Ogura, MD, Hirohisa Miura, MD, Atsuko Tsutsui, MD, Takeo Sato, MD, PhD, Takatoshi Nakamura, MD, PhD. Kitasato University, Department of Surgery

Background: Clinical use of absorbable adhesion barrier made of oxidized regenerated cellulose (INTERCEED) is reported in the field of obstetrics and gynecology to prevent adhesion ileus. Meanwhile, in the field of gastrointestinal surgery, sodium-hyaluronate / carboxymethylcellulose (Seprafilm) is reported to be used as an absorbable adhesion barrier. However, Seprafilm is difficult to use with the trocars in laparoscopic surgery.

Methods: We analyzed 50 patients who were performed laparoscopic colorectal surgery using INTERCEED from 2013 to 2014 in Kitasato University. We investigated maneuverability of INTERCEED for laparoscopic surgery. We used the VAS (Visual Analog Scale) for evaluation.

Results: We investigated the relationship between the length of the small incision and the ease of trimming, the ease of intraabdominal delivery, the ease of extent in surgical site and the stick to surgical site for the evaluation of maneuverability. Results showed that the mean was 9 cm or greater by VAS for all investigation factors.

Conclusion: We showed that INTERCEED has excellent maneuverability in laparoscopic surgery which the operating space is narrow. INTERCEED is an extremely valuable medical resource, and we think that the use of this material will be able to contribute extensively to the prevention of postoperative adhesions.