The Effect of Tissue Compression on Staple Line Failure

Introduction: Circular staplers are often used to form a gastrojejunostomy. However, leaks occur 0.1-3% of the time resulting in serious morbidity and mortality. The purpose of this study is to evaluate the effect of tissue compression on the acute strength of a stapled anastomosis.

Methods: Twenty-seven freshly harvested porcine stomachs and segments of small intestine were randomly assigned to three groups of 9, each set at different closed staple heights: Group A (2.5 mm), Group B (1.75mm), Group C (1.0 mm). Tissue compression (TC) was measured before circular stapled gastrojejunostomy was performed, while maximum intralumenal pressure (MIP) was determined following the formation of the anastomosis.


MIP reached >18 mm Hg in 18 of 20 (90%) of samples where TC was >6 PSI, compared to 3 of 7 (43%) of samples where TC was

Session: Poster

Program Number: P300

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