Background: Accurate identification of gastroesophageal reflux episodes is fundamental to the objective diagnosis of GERD. The diagnosis of GERD by multichannel intraluminal impedance (MII) is based on the detection of retrograde bolus propagation, irrespective of its pH. It is suggested that both the number and duration of acidic reflux episodes varies depending on the method of analysis, MII or pH monitoring. The ideal detection method is unknown.
Hypothesis: Multichannel impedance under estimates acid reflux episodes.
Design: Retrospective case series. Setting: Academic medical center.
Methods: 25 unselected patients (6 men, mean age 54 y) with foregut symptoms undergoing combined 24 hour catheter based MII-pH monitoring were studied. Every occurrence of esophageal pH drop
Program Number: P258