• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

SAGES

Reimagining surgical care for a healthier world

  • Home
    • COVID-19 Annoucements
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Who is SAGES?
    • SAGES Mission Statement
    • Strategic Plan, 2020-2023
    • Committees
      • Request to Join a SAGES Committee
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Full Committee Rosters
      • SAGES Past Presidents
    • Donate to the SAGES Foundation
    • Awards
      • George Berci Award
      • Pioneer in Surgical Endoscopy
      • Excellence In Clinical Care
      • International Ambassador
      • IRCAD Visiting Fellowship
      • Social Justice and Health Equity
      • Excellence in Community Surgery
      • Distinguished Service
      • Early Career Researcher
      • Researcher in Training
      • Jeff Ponsky Master Educator
      • Excellence in Medical Leadership
      • Barbara Berci Memorial Award
      • Brandeis Scholarship
      • Advocacy Summit
      • RAFT Annual Meeting Abstract Contest and Awards
  • Meetings
    • NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2023 Scientific Session Call For Abstracts
      • 2023 Emerging Technology Call For Abstracts
    • SAGES 2021 Annual Meeting
    • CME Claim Form
    • Industry
      • Advertising Opportunities
      • Exhibit Opportunities
      • Sponsorship Opportunities
    • Future Meetings
    • Past Meetings
      • SAGES 2021
      • SAGES 2020
      • SAGES 2019
      • SAGES 2018
    • Related Meetings Calendar
  • Join SAGES!
    • Membership Benefits
    • Membership Applications
      • Active Membership
      • Affiliate Membership
      • Associate Active Membership
      • Candidate Membership
      • International Membership
      • Medical Student Membership
    • Member News
      • Member Spotlight
      • Give the Gift of SAGES Membership
  • Patients
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Patient Information Brochures
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find a SAGES Member
  • Publications
    • SAGES Stories Podcast
    • SAGES Clinical / Practice / Training Guidelines, Statements, and Standards of Practice
    • Patient Information Brochures
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • SCOPE – The SAGES Newsletter
    • COVID-19 Annoucements
    • Troubleshooting Guides
  • Education
    • OpiVoid.org
    • SAGES.TV Video Library
    • Safe Cholecystectomy Program
      • Safe Cholecystectomy Didactic Modules
    • Masters Program
      • SAGES Facebook Program Collaboratives
      • Acute Care Surgery
      • Bariatric
      • Biliary
      • Colorectal
      • Flexible Endoscopy (upper or lower)
      • Foregut
      • Hernia
      • Robotics
    • Educational Opportunities
    • HPB/Solid Organ Program
    • Courses for Residents
      • Advanced Courses
      • Basic Courses
    • Video Based Assessments (VBA)
    • Robotics Fellows Course
    • MIS Fellows Course
    • Facebook Livestreams
    • Free Webinars For Residents
    • SMART Enhanced Recovery Program
    • SAGES OR SAFETY Video
    • SAGES at Cine-Med
      • SAGES Top 21 MIS Procedures
      • SAGES Pearls
      • SAGES Flexible Endoscopy 101
      • SAGES Tips & Tricks of the Top 21
  • Opportunities
    • SAGES Fellowship Certification for Advanced GI MIS and Comprehensive Flexible Endoscopy
    • Foregut Fellowship Certification
    • SAGES Research Opportunities
    • Fundamentals of Laparoscopic Surgery
    • Fundamentals of Endoscopic Surgery
    • Fundamental Use of Surgical Energy
    • Job Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
  • Store
    • SAGES Logo Products
    • “Unofficial” Logo Products
  • Log In

Systemic Immune Response and Clinical Results After Single Port Versus Conventional Laparoscopic Cholecystectomy: Prospective Nonrandomized Study

Hyung-Joon Han, MD, Sae-Byeol Choi, MD, Wan-Bae Kim, MD, Tae-Jin Song, MD, Sung-Ock Suh, MD, Sang-Yong Choi, MD, Chung-Yun Kim, MD, Jong-Han Kim, MD, Seong Heum Park, MD, Dong-Sik Kim, MD, Jin-Suk Lee, MD, Young-Chul Kim, MD. Department of Surgery, Korea University College of Medicine

Introduction

The benefits of laparoscopic surgery and technical advances could open the new chapter in the minimally invasive surgery. The tendency of minimizing surgical trauma encourages the use of new approaches in laparoscopic surgery. Patients benefit from diminished surgical trauma and maintained immune function after laparoscopic surgery.The objective of this study was to compare the systemic acute cytokine response, specifically interleukin (IL)-6, C-reactive protein, leukocytes subpopulations to conventional laparoscopic and single port laparoscopic cholecystectomy and clinical outcomes, including pain, in order to determine if there is an advantage of any of these approaches.

Method

From September 1, 2009 to December 31, 2009, 149 patients had been diagnosed with gallstones or gallbladder polyps at Korea University Hospital and 77 patients were enrolled after giving written informed consent. The 61 patients included in the study were selected from enrolled 77 patients among 149 consecutive patients with diagnosed gallstones or gallbladder polyp.

Results

Of the 61 patients, 26 were males and 35 were females. Then mean age of the patients was 45.9 ± 14.3 years. The median serum level of IL-6 in the single port group on the postoperative day 1 (13.89, 7.55-31.17 versus 10.74, 6.31-30.03 pg/ml) was slightly higher and slightly lower on preoperative day (2.94, 1.25-3.79 versus 3.45, 1.84-6.29 pg/ml) and postoperative day 2 (6.70, 4.90-17.85 versus 7.04, 4.99-19.09 pg/ml) than that of the conventional group, however, there was no significant difference between both groups (p=0.345). On postoperative day 2, the level of the single port group had increased to 28.33 mg/L (20.97-63.97), being still higher than that of the conventional group (19.47, 11.09-54.96 mg/L). There were significant differences in the consecutive serum level of CRP in each group (p<0.001).

Conclusion

In this study, we evaluated the clinical outcomes, pain scores, serum IL-6, CRP, and leukocyte subpopulations in 31 patients who underwent single port laparoscopic cholecystectomy, comparing with 30 patients who underwent conventional laparoscopic cholecystectomy. We demonstrated no differences in those variables between the single port and conventional laparoscopic groups, although the mean age in the conventional group, the mean operation time in the single port group, and postoperative 4 hour pain score in the single port group were higher than that of the other group. Considering that the higher age was related to less surgery-induced pain and the longer operation time was associated with higher level of IL-6, we suggest that surgical stress in the single port group might be inferior to the conventional group.


Session: SS18
Program Number: S106

41

Share this:

  • Twitter
  • Facebook
  • LinkedIn
  • Pinterest
  • WhatsApp
  • Reddit

Related

« Return to SAGES 2011 abstract archive

Our Mission

Innovate, educate and collaborate to improve patient care.

Recently, on SAGES…

Surgery is Safer with Vaccination 1

Addressing Religious Concerns About COVID-19 Vaccine

This may be a difficult subject matter for you and your patient to talk about.  Be assured, all major organized religious groups encourage and recommend the COVID-19 vaccine. Listed below are references and websites you can direct your patient towards to help them make an informed decision with regards to their religious concerns against the […]

SAGES Statement on AAPI Violence

The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) stands in solidarity with the Asian American and Pacific Islander (AAPI) community. In the summer of 2020, SAGES released a statement condemning the violence, racism, and hatred toward the Black community in the wake of George Floyd and Breonna Taylor’s murders. It is with great sorrow […]

Free SAGES Webinar: Lessons from COVID on Living and Thriving as Surgeons

SAGES recognizes that the COVID-19 pandemic has had a big impact on surgical practice and in surgeon wellness. SAGES’ Reimagining the Practice of Surgery Taskforce will present “Finding the Opportunities: Lessons from COVID and How We Live and Thrive as Surgeons”  to look at ways in which innovative leadership at various levels may help transform […]

Contact SAGES

Society of American Gastrointestinal and Endoscopic Surgeons
11300 W. Olympic Blvd Suite 600
Los Angeles, CA 90064 USA
[email protected]
Tel: (310) 437-0544

Find Us Around the Web!

  • Facebook
  • Twitter
  • YouTube

Important Links

SAGES 2022 Meeting Information

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals

 

  • taTME Study Info
  • Foundation
  • SAGES.TV
  • MyCME
  • Educational Activities

Copyright © 2022 Society of American Gastrointestinal and Endoscopic Surgeons