Deqing Wu, Zifeng Yang, Yong Li. Guangdong General Hospital , Guangdong Academy of Medical Sciences
Introduction: Laparoscopic technique has been widely used in the treatment of colorectal cancer, while playing its minimally invasive advantages, but also achieved a good effect of radical oncology. However, T4 colorectal cancer is not recommended laparoscopic surgery.
Methods: Retrospectively collected pT4 colorectal cancer data from 2006 to 2015 in Guangdong General Hospital, all cases were undergoing radical surgery.
Results: A total of 211 cases were enrolled in the pT4 group, including 101 cases of laparoscopic group, 110 cases of open group, conversion rate was 12.9%. There was no difference in baseline data (age, sex, BMI, ASA, etc.)(P <0.05). There was a significant difference between the two groups (p <0.05) in blood loss, postoperative complications and postoperative recovery index. In the pathologic T4a / b, combined-organ resection, postoperative recurrence, the laparotomy group had more cases, and there was a statistically significant difference between the two groups (p <0.05). The 3-and 5-year overall survival rates were 74.9% and 60.5% for the LAP group and 62.4% and 46.5% for the OPEN group (p = 0.060). Meanwhile, the 3-and 5-years disease- (P = 0.053) .IIIC stage, lymph node status, CA19-9 and adjuvant chemotherapy were independent prognostic factors affecting overall survival. The age, pT4a / b, IIIC stage, CA19-9 and adjuvant chemotherapy were independent influencing factors of disease-free survival.
Laparoscopic surgery for pT4 colorectal cancer surgery, it is not only in the play of its minimally invasive but also obtained with the similar long-term effect. But we need more multicenter, prospective, and large sample clinical studies to validate our findings.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 86489
Program Number: P249
Presentation Session: iPoster Session (Non CME)
Presentation Type: Poster