• Skip to main content
  • Skip to header right navigation
  • Skip to site footer

Log in
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
www.sages.org

SAGES

Reimagining surgical care for a healthier world

  • Home
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Awards
    • Who Is SAGES?
    • Leadership
    • Our Mission
    • Advocacy
    • Committees
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Committee Rosters
      • SAGES Past Presidents
  • Meetings
    • SAGES NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2026 Scientific Session Call for Abstracts
      • 2026 Emerging Technology Call for Abstracts
    • CME Claim Form
    • SAGES Past, Present, Future, and Related Meeting Information
    • SAGES Related Meetings & Events Calendar
  • Join SAGES!
    • Membership Application
    • Membership Benefits
    • Membership Types
      • Requirements and Applications for Active Membership in SAGES
      • Requirements and Applications for Affiliate Membership in SAGES
      • Requirements and Applications for Associate Active Membership in SAGES
      • Requirements and Applications for Candidate Membership in SAGES
      • Requirements and Applications for International Membership in SAGES
      • Requirements for Medical Student Membership
    • Member Spotlight
    • Give the Gift of SAGES Membership
  • Patients
    • Join the SAGES Patient Partner Network (PPN)
    • Patient Information Brochures
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find A SAGES Surgeon
  • Publications
    • Clinical / Practice / Training Guidelines, Statements, and Standards of Practice
    • Sustainability in Surgical Practice
    • SAGES Stories Podcast
    • Patient Information Brochures
    • Patient Information From SAGES
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • MesSAGES – The SAGES Newsletter
    • COVID-19 Archive
    • Troubleshooting Guides
  • Education
    • Wellness Resources – You Are Not Alone
    • Avoid Opiates After Surgery
    • SAGES Subscription Catalog
    • SAGES TV: Home of SAGES Surgical Videos
    • The SAGES Safe Cholecystectomy Program
    • Masters Program
    • Resident and Fellow Opportunities
      • MIS Fellows Course
      • SAGES Robotics Residents and Fellows Courses
      • SAGES Free Resident Webinar Series
      • Fluorescence-Guided Surgery Course for Fellows
      • Fellows’ Career Development Course
    • SAGES S.M.A.R.T. Enhanced Recovery Program
    • SAGES @ Cine-Med Products
      • SAGES Top 21 Minimally Invasive Procedures Every Practicing Surgeon Should Know
      • SAGES Pearls Step-by-Step
      • SAGES Flexible Endoscopy 101
    • SAGES OR SAFETY Video Activity
  • Opportunities
    • Fellowship Recognition Opportunities
    • SAGES Advanced Flexible Endoscopy Area of Concentrated Training (ACT) SEAL
    • Multi-Society Foregut Fellowship Certification
    • Research Opportunities
    • FLS
    • FES
    • FUSE
    • Jobs Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • OWLS/FLS
You are here: Home / Abstracts / Review of outcomes from a single center experience with endoscopic mucosal resection for intramucosal adenocarcinoma of the esophagus and Barrett\’s esophagus, A Canadian experience

Review of outcomes from a single center experience with endoscopic mucosal resection for intramucosal adenocarcinoma of the esophagus and Barrett\’s esophagus, A Canadian experience

Tami Yamashita, MD, FRCSC, Harry Henteleff, MD, MSc, FRCSC, FACS, FCCP, Drew Bethune, MD, MSc, FRCSC, FCCP, James Ellsmere, MD, MSc, FRCSC. Dalhousie University

Introduction. Endoscopic mucosal resection (EMR) is increasingly being used as first line treatment for Barrett’s esophagus (BE) with dysplastic changes and intramucosal adenocarcinoma (IMC). At our center, patients are selected for endoscopic therapy and surveillance for high-grade dysplasia and IMC using a collaborative approach between therapeutic endoscopists and thoracic surgeons. We hypothesize that our outcomes are consistent with the emerging literature supporting this strategy.

Methods. Between October 2010 to August 2014, 30 consecutive patients underwent EMR for BE with dysplastic changes and IMC. A retrospective chart review was performed on these patients to assess: complications, eradication of dysplasia, and progression of disease. EMR was performed using the Duette Multi-Band Mucosectomy device (Cook Medical, Bloomington, IN).

Results. Of the 30 study patients, 17 were referred with BE, 12 were initially referred for IMC, 1 was referred for palliative management of invasive adenocarcinoma. Of the group with BE, 15 patients had high-grade dysplasia (HGD), one patient had low-grade dysplasia and one had intermediate dysplasia. Median follow-up was 363 days.

Fifteen patients were referred with HGD, and complete eradication of dysplasia was achieved in 12 patients (80%). Three patients with HGD did not achieve pathologic remission: one died from acute leukemia, one was lost to follow-up, and one with a long segment HGD was referred for RF ablation therapy. None of the patients referred for EMR for dysplastic changes developed invasive esophageal cancer.

Of the 12 patients referred for IMC, 4 were found to have invasive adenocarcinoma based on the EMR specimen and were referred for esophagectomy. Eight patients with an EMR confirmed diagnosis of IMC were successfully managed with EMR and endoscopic surveillance, with complete eradication of dysplasia in all these patients.

Complications were minimal with 2 patients developing esophageal strictures, which were successfully managed with dilatation. There were no cases of perforation or post-operative hemorrhage.

Conclusion. Our multidisciplinary experience supports that EMR can be safely performed as a first line treatment for patients with BE with dysplastic changes and intramucosal adenocarcinoma (IMC).

34

Share this:

  • Click to share on X (Opens in new window) X
  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on LinkedIn (Opens in new window) LinkedIn
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Mastodon (Opens in new window) Mastodon
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on Bluesky (Opens in new window) Bluesky

Related


sages_adbutler_leaderboard

Hours & Info

11300 West Olympic Blvd, Suite 600
Los Angeles, CA 90064

1-310-437-0544

[email protected]

Monday – Friday
8am to 5pm Pacific Time

Find Us Around the Web!

  • Bluesky
  • X
  • Instagram
  • Facebook
  • YouTube

Copyright © 2025 · SAGES · All Rights Reserved

Important Links

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals