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You are here: Home / Abstracts / Resolution of Diabetes Mellitus, Hypertension, and Hyperlipidemia after Laparoscopic Vertical Sleeve Gastrectomy

Resolution of Diabetes Mellitus, Hypertension, and Hyperlipidemia after Laparoscopic Vertical Sleeve Gastrectomy

Iswanto Sucandy, MD, Gintaras Antanavicius, MD, FACS, Fernando Bonanni, MD, FACS

Abington Memorial Hospital, Department of Surgery

Introduction: Laparoscopic vertical sleeve gastrectomy (LSG) was initially performed as the first stage of biliopancreatic diversion with duodenal switch and is now considered a definitive procedure because of its promising early and midterm results. As a relatively new operation however, the effects of LSG on obesity-related comorbidities have not been adequately investigated. This study was designed to evaluate resolution or improvement of the common obesity-related comorbidities (diabetes mellitus, hypertension, and hyperlipidemia) after LSG.

Methods: A prospectively maintained database of all patients who underwent LSG between 2008 and 2011 was reviewed.

Results: A total of 131 consecutive patients (female : male = 98:33) were included with mean age of 49.4 years (range: 19-79), BMI of 48.9 kg/m2 (range: 34-84). The average number of preoperative comorbidities was 3.9 (range: 0-12). Mean operative time was 106 minutes (range: 48-212) without intraoperative complications. Among the common obesity-related comorbidities, hypertension was found in 55% of patients, followed by diabetes mellitus (33%), and hyperlipidemia (36%). At 1 year after LSG, the highest resolution was seen with diabetes mellitus (72%), followed by hypertension (55.5%), and hyperlipidemia (50%). All diabetic patients experienced improved control of their hyperglycemia (either complete resolution or less severe disease) at 18 months postoperatively. Significant improvements in hypertension and hyperlipidemia were seen in 36.1 % and 19.6 % of patients, respectively. Percentages of excess body weight loss (EBWL) at 1,3,6,9,12, and 18 months postoperatively were 19.3%, 31%, 44.5%, 50%, 57.3%, and 65.2%, respectively. No mortality occurred in this study.

Conclusions: Laparoscopic sleeve gastrectomy is an effective weight loss procedure with satisfactory resolution or improvement of diabetes mellitus, hypertension, and hyperlipidemia.


Session: Poster Presentation

Program Number: P404

260

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