Sulaiman Almazeedi, Salman Al-Sabah. Amiri Hospital
Type 2 diabetes mellitus (T2DM) comprises 90% of diabetics and is largely the result of excess body weight. There is rising evidence in the literature to suggest that laparoscopic sleeve gastrectomy (LSG) produces effective weight loss and improves obesity-related co-morbidities such as T2DM. The purpose of the study is to observe the effectiveness of LSG in the remission of T2DM.
Methods and Procedures
A retrospective study of 107 diabetic obese patients who underwent LSG at Al-Amiri Hospital from October 2008 to October 2012 was conducted. The pre and postoperative diabetic status, body mass index, and percent excess weight loss (%EWL) of the patients were retrieved and analyzed.
The mean age of the patients was 42 years±10.4 and 68% were females. Median preoperative BMI was 46kg/m2 (30– 87) and median postoperative follow up period was 18 (2 – 48) months. Pre and postoperative fasting blood glucose and HbA1C were measured. Resolution and improvement of T2DM was 53.3% (n=57) and 38.3% (n=41), respectively. The %EWL was 72% at 1 year and 73% at 4 years and median postoperative BMI was 33 kg/m2 (20-61). Duration based analysis showed that most of the resolved patients had diabetes for less than 5 years.
LSG resulted in total remission of T2DM in more than half of the patients and is more effective for the treatment of patients with short-term duration of the disease.