Plasma Levels of Svegfr2 Are Decreased and Svegfr1 Increased Early After Colectomy for Cancer; the Net Impact Is Decreased Binding of Free Vegf Which May Account for Increased Plasma Vegf Levels Early Postoperatively
Purpose : Plasma VEGF levels are elevated after minimally invasive colon resection (MICR) and may pose a danger for colon cancer (CRC) patients. It is thought that surgical wounds produce VEGF which enters the circulation. VEGF induces angiogenesis in wounds and tumors by binding to endothelial cell bound VEGF-Receptor 1 (VEGFR1) and VEGF-Receptor 2 (VEGFR2).… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Longterm Outcomes of Laparoscopic Surgery for Rectal Cancer
INTRODUCTION: Although surgeons are increasingly using a laparoscopic approach in rectal cancer surgery, its long-term outcomes have not yet been conclusively defined. In this study, we examine the longterm outcomes of laparoscopic surgery for rectal cancer at a single institution, with up to eleven years of follow-up.METHODS: We performed a retrospective review of a prospective… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally Invasive Approach to Left-sided Large Bowel Obstruction
Introduction: Self-expanding metallic stents (SEMS) are being used for “palliation” and as a “bridge" to surgery in obstructing colorectal disease. This approach may be associated with less morbidity and mortality than immediate operation for this surgical emergency. A laparoscopic approach is usually contraindicated due to bowel distention encountered in this acute situation. However, by relieving… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Comparison Wound Bacterial Contamination Between Open Colorectal Surgery and Laparoscopic Colorectal Surgery
PURPOSE: Many investigators reported the advantage of laparoscopic colorectal surgery for prevention of surgical site infection (SSI). To compare wound bacterial contamination between open colorectal surgery (OC) and laparoscopic colorectal surgery (LC).METHOD: Colorectal cancer surgery with no association of ileus was evaluated between 22 OC cases and 19 LC cases. Preoperatively, only mechanical preparation was… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Laparoscopic Surgery for Familiar Adenomatous Polyposis: Feasibility and Safety
Purpose: The role of laparoscopy in patient with familial adenomatous polyposis (FAP) has been controversial given its technical difficulty, high conversion rate, and complication rate. We present our experience of laparoscopic dissection and transection of rectum in the FAP patients.Methods: Consecutive 9 patients who underwent laparoscopic surgery for FAP were recruited. Eight patients combined with… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
A Prospective Study Comparing the Surgical Outcomes Between Laparoscopic Surgery for Transverse and Descending Colon Cancer and Laparoscopic Surgery for Other Colon Cancers.
Introduction: Several prospective randomized trials have demonstrated the long-term oncological safety of laparoscopic surgery for colon cancer. However, transverse/descending colon cancers were excluded from prior randomized controlled trials, mainly because of technical difficulties. This study was designed to compare surgical outcomes between laparoscopic surgery for transverse/descending colon cancers and that for other colon cancers, in… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Colorectal
Impact of Gender on Early Surgical Outcomes After Laparoscopic Surgery for Rectal Carcinoma.
Introduction: Controversies still persist regarding the appropriateness of laparoscopic surgery in patients with rectal carcinoma because of the uncertainty of long-term outcome, and of concerns over the safety of the procedure. Recently, several studies analyzing the risk factors of laparoscopic surgery for rectal carcinoma have been reported, and in some reports, male gender has been… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally Invasive Colorectal Resection Is Associated with a Rapid and Sustained Decrease in Plasma Epidermal Growth Factor Levels in the Colon Cancer Setting
Purpose : Epidermal Growth Factor (EGF) is a potent promoter of angiogenesis. Most colorectal adenocarcinomas (CRC) express the EGF-receptor and many make EGF as well. EGF is thought to independently stimulate tumor growth in addition to promoting tumor angiogenesis. Blood EGF levels have been shown to be elevated in CRC patients. The early impact of… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Can the Morbidly Obese Benefit From Laparoscopic Colorectal Resection?
OBJECTIVE: The aim of this study is to assess the feasibility and clinical outcomes of laparoscopic colorectal surgery (LC) in patients with body mass index (BMI) >40. METHODS: Prospectively accrued data for patients with BMI >40 (Group A) undergoing LC were compared with those for patients with BMI Session: Poster Program Number: P550 Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Minimally Invasive Colorectal Resection Is Associated with a Transient Increase in Plasma Hgf Levels Early After Surgery for Cancer
Purpose: Hepatocyte Growth Factor (HGF) is a potent angiogenic factor; preoperative blood levels have been shown to correlate with disease stage and prognosis in colorectal cancer (CRC) patients. In addition, some CRC’s express HGF receptor which suggests HGF might directly stimulate tumor growth. The impact of minimally invasive colorectal resection (MICR) on plasma HGF levels… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Plasma Angiostatin and Endostatin Levels Remain Unchanged for the First 3 Weeks After Colorectal Cancer Resection
Purpose: Angiostatin and endostatin are endogenous inhibitors of angiogenesis that have been shown to have anti-cancer effects. Major surgery has been associated with significantly elevated plasma VEGF and Angiopoetin 2 levels for the first 3 weeks after colorectal resection. Furthermore, human plasma from the second and third Post-operative week has been shown to stimulate in… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Is Pfannenstiel Better? Surgical Site Infections Following Laparoscopic-Assisted Colorectal Surgery
INTRODUCTION: Colorectal surgery has classically been associated with a high rate of surgical site infection (SSI) due to the contaminated nature of the operations. The most recent National Nosocomial Infections Surveillance (NNIS) System Report indicates overall rates of 11.3%. However, other investigators have reported rates as high as 26%. It has been proposed that the… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Title: Management of Intraoperative Complication During Laparoscopic Proctectomy for Submucosal Rectal Tumor
INTRODUCTION: This video demonstrates a laparoscopic proctectomy in a 51 year old female who presented with a symptomatic sub-mucosal anterior rectal lesion suspected of being a GIST tumour. The video illustrates work up, operative technique, and laparoscopic management of this patient; including two intra-operative complications that occurred during the pelvic dissection.PROCEDURE: This case presentation demonstrates… Continue Reading
- Topic:
- Colorectal
Laparoscopic Total Mesorectal Excision and Coloanal Anastomosis for Carpeting Villous Polyp of the Rectum
INTRODUCTION: This video demonstrates a step-by-step approach to laparoscopic total mesorectal excision and coloanal anastomosis. Emphasis is placed on the features that respect the same oncologic principles as open surgery.PROCEDUREThis case features a 38 year old man with a carpeting tubulovillous adenoma of the rectum extending from the dentate line to 20 cm from the… Continue Reading
- Topic:
- Colorectal
Cecectomy May Be a Superior Alternative to Right Hemicolectomy for Select Benign Cecal Polyps
Introduction: Colorectal cancer usually arises from polyps. Patients with endoscopically-unresectable polyps frequently undergo hemicolectomy. Selected patients with very proximal benign cecal polyps may be amenable to cecal cap resection with preservation of the ileocecal valve. The purpose of this study was to compare outcomes at our institution of patients undergoing cecectomy vs. right hemicolectomy for… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal