Cardiovascular Differences Within the Omentum of Morbidly Obese Diabetic Patients
Background: The metabolic syndrome describes the association between obesity and a host of co-morbidities including insulin resistance, hypertension, dyslipidemia, and cardiovascular (CV) disease. Adipokines produced from omentum increase the inflammatory state and reportedly contribute to the risk of CV disease. This study examines the genetic differences in the omental tissue of morbidly obese diabetic and… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Adiponectin and Leptin in the Bariatric Patient
Background: Through relatively unknown mechanisms, bariatric surgery can resolve type 2 diabetes in morbidly obese patients. Potentially, pre- and post-operative changes in adiponectin and leptin expression are involved in this process. This study attempts to identify differences in gene expression in diabetic and non-diabetic patients undergoing bariatric surgery with regards to adiponectin and leptin. Methods:… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Laryngopharyngeal Reflux (lpr): Pathophysiologic Evidence of Two Different Subtypes
Introduction: Laryngo-pharyngeal reflux (LPR) refers to symptoms caused by backflow of gastric contents to the larynx and pharynx. Concurrent pH recordings at increasing distances above the LES are reported to show a linear decrease in acid exposure as the distance from the LES increases. While abnormal distal esophageal acid exposure is common in patients with… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
The Effect of Inhaled Lps on the Development of Bronchiolitis Obliterans.
Introduction: Gastroesophageal reflux-associated chronic aspiration contributes to the development of various lung disease processes including chronic pulmonary allograft dysfunction, as manifested by the histologic finding of bronchiolitis obliterans (BO). The TLR-4 innate immune pathway is thought to play a role in these processes and may be activated by bacteria within the gastric contents. Here we… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Differential Expression of Mmp-2 in the Gastrohepatic Ligament of the Gastroesophageal Junction
Introduction: Ligamentous attachments maintain the normal anatomical position of the gastroesophageal (GE) junction. Failure of these elastic ligaments through an alteration in collagen synthesis, deposition and metabolism may be a primary etiology of hiatal hernia formation. Differential expression of zinc-dependent matrix metalloproteinases (MMPs) is largely responsible for collagen remodeling. The purpose of this study was… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Basic Science
Human Monocyte Activation By Biologic and Biodegradable Meshes in Vitro
INTRODUCTION: We hypothesize that various biologic and biodegradable meshes (BM) differentially induce macrophage (MØ) activation in vitro. Inflammation and wound healing play critical roles in the integration of biologic and biodegradable meshes (BM) at the sites of hernia repair. Macrophages (MØ) are the key cells controlling inflammation and wound healing. Interleukin-1beta (IL-1b), IL-6, and IL-8… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Basic Science
Detail Analysis of Vessel Sealing Perfomance of Bipolar Vessel Sealing System for Laparoscopic Surgery
INTRODUCTION: Vessel sealing devices of 5 mm in diameter for laparoscopic surgery provide only a small breadth of sealing area. Therefore, various double sealing techniques have been tried to enhance bursting pressure of the sealed vessels by surgeons. However, there have been no reports to reveal which technique achieved best performance of vessel sealing. Those… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Hepatic Adiponectin and Leptin in Morbidly Obese Patients
Background: Pathologically, hepatic changes are common in morbidly obese patients. Insulin resistance impacts the pathogenesis of non-alcoholic fatty liver disease and may potentiate the progression of non-alcoholic steatohepatits and fibrosis. This study investigates the impact of leptin and adiponectin in morbidly obese diabetic and non-diabetic patients with regards to histopathological hepatic changes. Methods: Twenty morbidly… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Basic Science
Serum Leptin Levels Are Inversely Correlated with Omental Gene Expression of Adiponectin and Are Markedly Decrease After Laparoscopic Gastric Bypass Surgery
Adipose tissue is the most abundant endocrine tissue in the body, producing leptin, a hormone important in regulating hunger, and adiponectin, a hormone involved in insulin sensitivity and inflammation. The aim of this study was to assess the impact of gastric bypass surgery (GBS) on leptin levels and its relation to omental adiponectin expression. Methods:… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Basic Science
No Hemodynamic Difference Between NOTES and Endoscopy Over Short Time Period
Introduction: Natural Orifice Translumenal Endoscopic Surgery (NOTES) promises decreased invasiveness by performing intra-abdominal procedures while avoiding the abdominal wall. Data from a randomized blinded study showed significant divergence of heart rate and diastolic blood pressure for NOTES animals compared to laparoscopy animals. We compared animals undergoing diagnostic or interventional NOTES with animals undergoing standard endoscopy… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Weight Loss Induced By Laparoscopic Bariatric Surgery Is Associated with a Reduction in Autonomic Responsiveness
Introduction: In the face of high caloric intake and low levels of physical exertion, obesity induces sympathetic nervous system activation. This increased autonomic activity is manifested as higher blood pressure in obese patients, and as a result, excess body weight is associated with increased cardiovascular morbidity. Furthermore, it has been shown that when patients lose… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Retrospective Analysis of Resected Primary Colorectal Cancer Revealed No Correlation Between Node Harvest and Node Involvement
Introduction: The study aims to analyze the correlation between lymph node harvest (LNH) and node involvement (LNI) in resected primary colorectal cancer specimens. Patients & methods: Retrospective analysis. The study period is Jan 2002 – Dec 2006 (5y). The data were obtained from medical records. The patient inclusion criteria were resection of primary CRC including… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Role of Initial Clinical Assessment in the Diagnosis of Acute Diverticulitis
Introduction: This paper aims to determine the diagnostic accuracy of initial clinical assessment in the diagnosis of acute diverticulitis (AD). Patients and methods: Retrospective analysis. Patients admitted to the surgical unit via A&E between Apr 2002 and March 2006 inc. (4y) were identified using the International Code of Diseases (ICD-10 version 2007) coding system. Exclusions… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Laparoscopic Resection of Lymphangioma of the Small Bowel Mesentery in an Adult
A 32-year-old female presented for Colorectal Surgery consultation regarding an 18-month history of vague left-sided abdominal pain, intermittent bloating, frequent stools, and occasional passage of mucus. Her laboratory work-up was negative. CT scan of the abdomen and pelvis revealed a "mass in the small bowel mesentery". She had no chronic medical issues and had no… Continue Reading
- Type:
- Posters
- Topic:
- Colorectal
Ab Prep a New Colon Cleansing
AB Prep: colon cleansing made easierWith the colonoscopy being the main procedure that evaluates and prevents colon cancer; efforts to make the experience tolerable and pleasant has always been a priority and a challenge.In the United States out of all the people meeting the criteria for screening colonoscopy only 35% of the people actually undergo… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Colorectal