Chronic Aspiration Shifts the Immunue Response from Th-1 to Th-2 in a Murine Model of Asthma
Chronic aspiration associated with gastroesophageal reflux disease (GERD) is thought to play a substantial role in the development of asthma, the incidence of which is dramatically increasing in industrially developed countries. The majority of data examining the association between aspiration and asthma has been obtained from epidemiological studies, which show that between 50 and 90%… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
C-reactive protein concentrations before and after gastric bypass surgery inversely correlate with omental gene expression of adiponectin.
Adipose tissue is a key regulator of C-reactive protein (CRP), an inflammatory marker linked to atherosclerosis. Adiponectin, the most abundant adipokine is also an importantl factor involved in the inflammatory state of obesity. The aim of the study was to assess the impact of gastric bypass surgery (GBS) on the CRP levels and its relation… Continue Reading
- Type:
- Podium Presentations
- Topic:
- Basic Science
Bile reflux induced mutagenesis on esophageal epithelium in an animal model and its effect in cell signaling
BILE REFLUX INDUCED MUTAGENESIS ON ESOPHAGEAL EPITHELIUM IN AN ANIMAL MODEL AND ITS EFFECT IN CELL SIGNALING Ben Selvan MS, Anu Korula MD, Anoop Ramachandran PhD, Jaya kumar MSc, Sathish Kumar MSc, George MS, Christian Medical College ,Vellore Background: . Bile reflux has been suggested to have a mutagenic effect on esophageal epithelium. However, signaling… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science