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Multidisciplinary Approach For Management Of Necrotizing Pancreatitis: A Case Series

Prabhu Senthil- Kumar, MD, Waed Alswealmeen, MD, Qi Yan, PhD, Paul O’Moore, MD, Todd Braun, MD, Daniel Ringold, MD, Orlando Kirton, MD, Thai Vu, MD. Abington Memorial Hospital

Introduction: Necrotizing pancreatitis is often a devastating sequelae of acute pancreatitis. Historically several approaches have been described with variable outcome. Open necrosectomy is associated with higher morbidity (95%) and mortality (25%). Endoscopic necrosectomy often is tolerated well but associated with stent migration and multiple procedures. Video-assisted retroperitoneal debridement is tolerated well but associated with severe bleeding if adjacent blood vessels are injured during the procedure leading to severe complications

Methods: In our series, We perform a step up approach by involvement of a multidisciplinary group consisting of general surgeons, gastroenterologists, Infectious disease physicians, critical care internalist, interventional radiologist and nutritional services to formulate a management plan. The necrotized pancreas is initially drained with an IR guided drain, fluid cultures sent for microbiology and treatment with appropriate antibiotics if deemed necessary. The drain is gradually upsized to a 24 Fr sized drain to form a well-defined tract for surgical debridement; A pre-operative CT scan of the abdomen with IV contrast to access the location and proximity of the vasculature around the necrotized pancreas. A collaboration with the interventional radiologist to discuss possible IR embolization of splenic artery prior to surgical debridement. The patient would then undergo video assisted retroperitoneal pancreatic necrosectomy and a sump drain left in-situ at the pancreatic fossa. Post-operative management in the surgical ICU would be lead by the critical care internalist.

Results: Three patients were managed by this multidisciplinary approach with excellent outcomes. One patient underwent preoperative IR embolization followed by surgical debridement; second patient underwent embolization immediately following debridement; one patient did not require any embolization but had IR on standby if needed to intervene. Post-operatively all three patients recovered well. They all were tolerating good oral intake and were discharged to rehabilitation facilities.

Conclusion: Our preliminary experience demonstrates that  an early multidisciplinary plan by various subspecialties  can result in a pragmatic and successful approach to this potentially catastrophic condition.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 87691

Program Number: P536

Presentation Session: iPoster Session (Non CME)

Presentation Type: Poster

58

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