Kai Li, Zhangyuanzhu Liu, Dexin Chen, Weisheng Chen, Wei Jiang, Xiumin Liu, Ziming Cui, Zhiyao Wei, Zhiming Li, Yuliang Huang, Jun Yan, MD. Department of General Surgery, Nanfang Hospital, Southern Medical University
Background: Inferior mesenteric artery lymph nodes (253 lymph nodes) metastasis occurs in approximately 0.3 to 13.9% according to different T stage in rectal cancer, which is an important prognostic factor after curative resection for rectal cancer. The aim of this study was to evaluate the independent risk factors of 253 lymph nodes metastasis in rectal cancer
Methods: A total of 200 patients who underwent curative resection of the rectal cancer between January 2014 and August 2017 were selected. The patients were classified into 2 groups: 253-positive group (n = 18) and the 253-negative group (n = 182). The status of 253 lymph nodes were analyzed using univariate and multivariate analysis
Results: The rate of 253 lymph nodes metastasis in our study was 9%. Univariate analysis revealed that the risk factors of 253 lymph nodes metastasis were as follows: Mucinous adenocarcinoa and poorly differentiated (p=0.025); depth of tumor invasion (p=0.013); 251 lymph nodes positive (p<0.001); 252 lymph nodes positive (p<0.001); the number of 253 lymph nodes harvested (p=0.003). After multivariate regression analysis, only 251 lymph nodes positive (OR, 7.627; 95%CI, 1.664-34.976; p=0.009), 252 lymph nodes positive (OR, 5.273; 95%CI, 1.457-19.081; p=0.011); the numbers of 253 lymph nodes harvested (OR, 1.255; 95%CI, 1.082-1.454; p=0.003) were identified as independent risk factors of 253 lymph nodes metastasis in rectal cancer.
Conclusions: The status of 251 and 252 lymph nodes metastasis, and the numbers of 253 lymph nodes harvested were identified as independent risk factors of 253 lymph node metastasis in rectal cancer.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 87384
Program Number: P224
Presentation Session: iPoster Session (Non CME)
Presentation Type: Poster