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Melanosis Coli In Irritable Colon Syndrome Patients Who Is Not Using Laxatives

Sabahattin Destek, MD1, Vahit Onur Gul, MD2, Serkan Ahioglu, MD3. 1Bezmialem Foundation University School of Medicine Dragos Hospital General Surgery Department, 2Edremit State Hospital General Surgery, 3Edremit State Hospital

BACKGROUND: Melanosis coli (MC) is a benign condition caused by the accumulation of dark pigments in macrophages in the colonic mucosa. Usually incidentally find out in endoscopic examination. Accumulation of melanin, hemosiderin, ferrum sulfate, most frequently lipofuscin pigments in macrophages in the colonic mucosa is occurred. It has been reported to occur in 73% of Irritable Bowel Syndrome and chronic constipation patients that are users of anthraquinone laxatives.

METODS: In this presentation it’s presented that our irritable bowel syndrome patients without using anthraquinone laxatives or herbal tea have diagnosed MC.

RESULTS:Thirty six years old female patient was admitted to our clinic complaints about 3 years of intermittent abdominal pain, swelling of the abdomen, inability to fully emptying of colonic content and indigestion. Patient was going to the toilet every day and did not use laxatives. Biochemical parameters were normal. No pathology was found in stool examination. Reflux esophagitis, helicobacter pylori (+) and pangastritis are revealed in upper gastrointestinal endoscopy. In her colonic mucosa lower gastrointestinal endoscopy founded brown colored areas and internal hemorrhoidal disease. MC was detected in her histopathological examination. Treatment was initiated with a fiber-rich diet and again tried to gain a regular bowel habit. Patients were taking in followed up.

CONCLUSION: MC that is considered to be benign in previous studies usually seen in patients with chronic constipation problems and using the anthraquinone laxatives. However, as shown in our case, MC can be seen in irritable bowel syndrome without using of laxatives and herbal teas.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 80912

Program Number: P163

Presentation Session: Poster (Non CME)

Presentation Type: Poster

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