M A Gok, S J Ward, M M Sadat, U A Khan. Macclesfield District General Hospital
Introduction Colorectal Cancer (CRC) is the 3rd common cancer in the UK in men & women, accounting for 13% on new cancer cases in 2010 (incidence of 40695). Surgery in the main treatment & usually undertaken within 6 months of presentation. The aim of the study is to assess colorectal malignant resections at a single institution.
Materials & Methods This is a retrospective study carried out since January 2007 at Macclesfield District General Hospital. Descriptive demography, co-morbidities, histopathology and surgical outcomes were evaluated for all malignant colorectal resections.
CRC resections (n=740) | |
Ages (yrs) (mean ± SE) | 71.1 ± 0.4 |
Sex (M : F) | 406 : 334 |
ASA (median) | 2 |
Weight (kg) (mean ± SE) | 73.9 ± 0.8 |
BMI (mean ± SE) | 25.9 ± 0.2 |
Appendix / Ileum (n) | 19 |
Caecum (n) | 148 |
Ascending colon (n) | 60 |
Transverse colon (n) | 82 |
Descending colon (n) | 22 |
Sigmoid (n) | 157 |
Rectosigmoid (n) | 40 |
Rectum (n) | 212 |
Operation Time (min) (mean) | 155.3 ± 2.6 |
Small bowel length (mm) | 101.0 ± 5.2 |
Large bowel length (mm) | 263.7 ± 13.4 |
LN harvest (median ± IQR) | 14 ± 4 |
Diverticulosis (n) | 161 |
IBD (n) | 15 |
Synchronous tumours (n) | 108 |
Ileostomy/colostomy | 211 |
LOS (days) (median ± IQR) | 9 + 3.5 |
Survival rates (1st, 3rd & 5th yrs) (%) | 87.8%, 75.1%, 68.6% |
Dukes A (1st, 3rd & 5th yrs) (%) | 96.1%, 90.9%, 84.0% |
Dukes B (1st 3rd & 5th yrs) (%) | 90.8%, 83.5%, 79.2% |
Dukes C (1st, 3rd & 5th yrs) (%) | 82.5%, 61.2%, 53.8% |
Discussion Left sided colon cancer represents almost 2/3 rds (58.2 %) of the CRC. There is predominance of CRC in men. Survival rates drop with progression of disease (Dukes / TNM classification). CRC cancer should be managed in the multi-disciplinary setting.