Ke Gong, MD, Nengwei Zhang, MD, Bin Zhu, MD, Jirun Peng, MD, Dexiao Du, MD, Buhe Amin, MD. Beijing Shijitan Hospital, Capital Medical University
Objective: To evaluate laparoscopic sleeve gastrectomy (LSG) to treat the patients suffering from metabolic disease.
Methods: Thirty-two patients suffering from metabolic disease were selected to undergo LSG surgery and were enrolled at Beijing Shijitan Hospital between January 2012 to January 2017.The body mass index(BMI), fasting plasma glucose(FPG), glycosylated hemoglobin (HbA1c),serum triglyceride, serum cholesterol and blood pressure of all patients were measured before and at 6 months after surgery. The results were collected and analyzed.
Results: 32 patients suffered from metabolic disease undertook LSG surgery successfully(a mean age of 34 years), 12 were male and 20 were female. All of 32 patients suffered from obesity and the mean BMI of them was 40.61±7.66 kg/m2 before surgery. Among them, 19 patients had type 2 diabetes mellitus (T2DM), 23 patients had hypertriglyceridemia (HTG), 7 patients had hypercholesterolemia (HC) and 16 patients had hypertension. The mean BMI of 32 patients at 6 months after surgery was 30.78±5.51 kg/m2 and decreased significantly (P<0.05). The mean excess weight loss(EWL%)of 32 patients was 68.97%±26.68%(17%~120%)at 6 months after surgery. The average levels FPG,HbA1c of 19 T2DM patients at 6 months after surgery were 6.52±2.15mmol/L, 6.89%±1.34% and were lower than those before surgery (3.54±2.01mmol/L, P=0.000;1.30%±0.88%, P=0.000). The average serum triglyceride of 23 HTG patients decreased significantly at 6 months after surgery compared that before surgery (2.44±0.67mmol/L vs. 1.62±0.40 mmol/L, P=0.000). The mean serum cholesterol of 7 HC patients at 6 months after surgery was lower than that before surgery (0.82±0.67 mmol/L, P=0.000,) and was in normal range. The blood pressure of 16 hypertensive patients recovered to the normal range at 6 months after surgery. 32 patients were followed up for 6~28 months, an average period of 14 months. No major complication was found in all patients.
Conclusions: This research concludes that LSG is safe and effective to treat the patients who suffered from metabolic disease including obesity, T2DM, HTG, HC and hypertension. The further studies with larger samples are needed.
Keywords: Sleeve gastrectomy;obesity; type 2 diabetes; hypertension; hyperlipidemia
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 86205
Program Number: P635
Presentation Session: iPoster Session (Non CME)
Presentation Type: Poster