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Laparoscopic Management of Pancreatic Neuroendocrine Tumors – An Experience from a Tertiary Care Centre in South India

P Senthilnathan, R Parthasarathi, S Rajapandian, P Praveen Raj, Anand Vijai, V P Nalankilli, G Srivatsan, Sandeep Sabnis, C Palanivelu. GEM Hospital & Research Centre

Background: Pancreatic neuroendocrine tumors are rare with an incidence of 0.30/100,000 persons in the general population. Traditionally pancreatic neuroendocrine tumors have been managed with open surgical approach but with increasing experience laparoscopic management of pancreatic neuroendocrine tumors has evolved in the last decade. With the advent of intraoperative ultrasound identification of lesions during surgery has greatly improved. We share our experience of laparoscopic management of such lesions.

Materials and methods: All patients diagnosed with pancreatic neuroendocrine tumors between 2010 and 2015 were included in this study irrespective of stage of the disease.

Results: 24 patients were diagnosed as pancreatic neuroendocrine tumor. Out of these 24 patients 13 patients underwent surgical management. Out of the 13 patients 11 underwent surgery by laparoscopic approach and 2 underwent surgery by open approach. 4 patients underwent pancreas preserving resection of first part of duodenum. 1 patient underwent enucleation. 1 patient underwent first part of duodenum resection along with distal pancreatectomy. 3 patients underwent pancreaticoduodenectomy. 3 patients underwent distal pancreatectomy. 1 patient underwent central pancreatectomy. On hispopathological examination, all were R0 resection. 1 patient received conventional adjuvant chemotherapy. 2 patients received mTOR inhibitor. 1 patient received PRNT.

Conclusion: Laparoscopic management of pancreatic neuroendocrine tumors is comparable to open surgery. Intraoperative ultrasound is an important modality for identification of lesions for laparoscopic approach. If adequate expertise is available laparoscopic approach towards surgical management of pancreatic neuroendocrine tumors should be considered.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 80845

Program Number: P475

Presentation Session: Poster (Non CME)

Presentation Type: Poster

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