Evaluation of Surgical Stress response after Laparoscopic Cholecystectomy in Elderly Patients

Luciana Fialho, MD, Fernando Madureira, SAGES, Msc, Phd, Antonio Carlos Garrido, TCBC, MsC, Phd


Currently the growth of the elderly population is a worldwide phenomenon. And due to the increasing number of surgical procedures in this populace, this population represents an important segment within the surgery not only by their physiological peculiarities, but also by its numerical representation. It – is paramount to understanding the physiological response resulting from surgical stress in this group of patients to have safe surgical option for this population group. The objective of this study is to evaluate the response to trauma in the elderly after laparoscopic cholecystectomy.


Prospective study of consecutive patients of both sexes, conducted at Hospital Gaffrée and Guinle, Rio de Janeiro, Brazil. Patients were randomized into 2 groups of 30 individuals: group (A) elderly patients aged 60 years or older, and group (B) patients aged 18-59 years . Inclusion: diagnosis of uncomplicated cholelithiasis and low degree of surgical risk. The patients underwent laparoscopic cholecystectomy and accomplished collection of interleukin 6 (IL-6) during anesthetic induction, 3 hours and 24 hours after surgery, as well as analysis of the PCR after 3 hours of surgery.

Total of 60 patients. Group A: mean age 67 years (60-86), 83% women.Group B: mean age 46 (18-59), 80% women. Values ??of IL-6 induction, 3 hours and 24 hours – sample: Group A (18.04) (56.84) (24.7) Group B (7.55) (19.85) (26.9). CRP Group A (1.44) Group B (6.33).

There was no statistically significant difference in the response to trauma after laparoscopic cholecystectomy among the group of young and elderly patients.

Session: Poster Presentation

Program Number: P556

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