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Esophageal motility in 100 patients with end-stage lung disease

Takahiro Masuda, Saurabh Singhal, Sreeja Biswas Roy, Michael Smith, Jasmine Huang, Sumeet K Mittal, Ross M Bremner. Norton Thoracic Institute; St. Joseph’s Hospital and Medical Center

INTRODUCTION: Advanced lung disease has been reported to be associated with gastro-esophageal reflux disease (GERD). Aim of this study is to assess the prevalence of esophageal motility disorders and pathological reflux in patients undergoing lung transplant.

METHODS AND PROCEDURES: All patients who undergo lung transplant at our institution and entered in a prospective database. After IRB approval the database was queried to identify 100 patients who underwent non emergent transplant between Jan. 2015 to Jun. 2016 and had pre-operative esophageal testing available. Manometry studies were reanalyzed using Chicago Classification v 3.0.

RESULTS: A total of 158 patients underwent non-emergent lung transplant during the study period of which esophageal manometry was available for 100 patients. Mean age was 60.8 ± 9.9 years with 36 females and a BMI of 26 ± 5.2. Fifty six patients had esophageal dysmotility: 3 achalasia, 3 EGJ outflow obstruction, 3 jackhammer esophagus, 1 distal esophageal spasm, 7 absent contractility, 35 ineffective esophageal motility, 4 fragmented peristalsis. EGJ morphology showed 61 type I, 18 Type II, 15 Type IIIa and 6 Type IIIb EGJ morphology.

CONCLUSIONS: There is a very high prevalence of esophageal motility disorders and pathological reflux disease in patients undergoing lung transplant at our center. These abnormalities need to be carefully evaluated when considering patients for lung transplantation.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 80545

Program Number: P352

Presentation Session: Poster (Non CME)

Presentation Type: Poster

196

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