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Eosinophilic colitis, what effect the effect of immune system deficiency in the etiology?

Sabahattin Destek, MD1, Vahit Onur Gul, MD2, Serkan Ahioglu, MD3. 1Bezmialem Foundation University School of Medicine Dragos Hospital General Surgery Department, 2Edremit State Hospital General Surgery, 3Edremit State Hospital

BACKGROUND: Eosinophilic colitis is a rare disease in digestive system. Genetic predispositions, food intolerance, increase of immunologic response are all included in pathophysiology of this disease. Allergic conditions associated with this disease frequently. Main symptoms are mucoid diarrhea and abdominal pain. Eosinophilic infiltration in endoscopic examination is diagnostic criteria.

METHODS:In this report we assume that eosinophilic colitis should be considered for differential diagnosis of abdominal pain and chronic mucoid diarrhea.

RESULTS: Forty-two years old female patient was admitted to our hospital with complaining of abdominal pain, weight loss and 10 times a day diarrheal attacks. In her history, she has pollen allergy and discomfort when she eats nuts and dairy products. She is taking Hashimoto’s thyroiditis treatment. In her biochemical examination there is anemic findings and increasing RF value. In stool examination mucus, leukocytes and erythrocytes are seen but not parasites. Pangastritis is detected in her upper GIS endoscopic examination. Aphthous erosional lesions in right colon and caecum are detected in lower GIS examination. Eosinophilic pericriptitis in right colon and caecum are seen in histopathological examination of endoscopic biopsies. Food elimination and short time steroid treatment is started. Patient’s symptoms are relieved. Recurrence is not seen in follow-up.

CONCLUSIONS: Symptoms of EC are not specific so it’s confused with other digestive diseases. It’s commonly seen in atopic people. Diagnosis begins with suspicious of disease. Evaluation of biopsies from the digestive tract and exclusion of other causes is diagnostic. Eosinophilia could not be in blood. Main treatment is food elimination.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 80913

Program Number: P152

Presentation Session: Poster (Non CME)

Presentation Type: Poster

43

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