Fernando Munoz, MD, Cesar Munoz, MD, Fernando Pimentel, MD, Dannae Turiel, RN, Cecilia Gomez, RN, Sergio Guzman, MD, Luis Ibanez, MD, Alex Escalona, MD
Digestive surgery department, Pontificia Universidad Catolica de Chile
INTRODUCTION: The Endoscopic Duodenojejunal Bypass Liner (DJBL, EndoBarrier®, GI Dynamics, Inc., Lexington, MA) has proved to be effective and safety in treatment of Diabetes Mellitus and obesity. The aim of the study is to evaluate weight loss with the use of DJBL in patients with grade I obesity.
METHODS AND PROCEDURES: This study was approved by the ethics committee of the institution. All the included patients signed an informed consent for the use of their data.Data were recorded of DJBL implanted patients with a BMI between 30 to 34.9 kg/m2 from November 2010 to June 2012. We analized demographics, clinical and implantation variables, comorbidities, morbidity, weight loss during follow-up.
RESULTS: 29 patients were included, 1 patient was not implanted by a short duodenal bulb. 62% was female and 38% was male. The median age was 42 years (R: 21 – 70), the median preimplantation weight was 91 kg. (R: 71 – 114) with a median BMI of 32 kg/m2 (R: 30 – 35). The comorbidities was diabetes at a 20,7% of the patients, 34,5% insulin resistance and 34,5% has high blood pressure. Two patients had a no programmed explant (one for device displacement and one mild upper gastrointestinal bleeding). No patients had a serious morbidity. The median weight after 3 months of treatment was 79,5 kg (R:64 – 102) and BMI 28,5 kg/m2 (R: 25 – 32) with a percentage of excess weight lost (%EWL) 35,43% (p < 0.001). The median weight and BMI after 6 months of treatment was 78 kg (R: 64 – 100) and 29 kg/m2 and the %EWL was 32% (p < 0.002). The median weight at explant in patients who completed one year of treatment was 83 kg (R: 61-97) and BMI 27.3 kg/m2 (R: 23 to 30) with a %EWL of 40,53% (p<0,027)
CONCLUSION: In this study, the DJBL shows to be safety and effective in weight loss for patients with obesity grade I.
Session: Poster Presentation
Program Number: P457
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