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COMPARISON OF OUTCOMES BETWEEN LAPAROSCOPIC VS OPEN LIVER RESECTION FOR INTERMEDIATE STAGE (BCLC B) HEPATOCELLULAR CARCINOMA

Avril P. David, MD1, YoungRok Choi, MD2, Ho-Seong Han, MD2, Yoo-Seok Yoon2, Jai Young Cho2. 1Rizal Medical Center, Pasig City, Philippines, 2Seoul National University Bundang Hospital, South Korea

Introduction: The Barcelona Clinic Liver Score (BCLC) currently limits hepatic resection only for small, solitary tumors measuring 2-3cm with no signs of portal hypertension (PHT) or macrovascular invasion. The aim of this study is to show the benefit of surgical resection, and to compare the peri-operative and long-term outcomes between laparoscopic liver resection (LLR) and open liver resection (OLR) for hepatocellular carcinoma (HCC) classified as intermediate stage (B) under BCLC.

Methods and Procedures: From 2004 to 2013, 49 patients staged as intermediate (BCLC B) and who underwent hepatic resection was included. These patients were divided into LLR or OLR. Demographics, tumor characteristics, recurrence rates and over-all survival were compared between the 2 groups.

Results: 49 patients were included and grouped into LLR (n=28) and OLR (n=21). The average tumor number was 2±1 for both groups, while the mean tumor size was 4.1cm and 4.9cm for the LLR and OLR group, respectively. When compared with OLR, LLR had lower post-operative complication rates (14.3% vs 33.3%, p=0.118) and shorter hospital stay (9 vs 21 days, p=0.103), although the difference was not statistically significant. Overall, recurrence-free and disease-free survival was comparable between LLR and OLR.

Conclusion: LLR showed comparable outcomes compared to OLR in the treatment of HCC staged BCLC B. Thus, LLR as well as OLR can be considered in selective patients in the BCLC B group.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 88230

Program Number: P531

Presentation Session: iPoster Session (Non CME)

Presentation Type: Poster

42

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