• Skip to main content
  • Skip to header right navigation
  • Skip to site footer

Log in
  • Search
    • Search All SAGES Content
    • Search SAGES Guidelines
    • Search the Video Library
    • Search the Image Library
    • Search the Abstracts Archive
www.sages.org

SAGES

Reimagining surgical care for a healthier world

  • Home
    • Search
    • SAGES Home
    • SAGES Foundation Home
  • About
    • Awards
    • Who Is SAGES?
    • Leadership
    • Our Mission
    • Advocacy
    • Committees
      • SAGES Board of Governors
      • Officers and Representatives of the Society
      • Committee Chairs and Co-Chairs
      • Committee Rosters
      • SAGES Past Presidents
  • Meetings
    • SAGES NBT Innovation Weekend
    • SAGES Annual Meeting
      • 2026 Scientific Session Call for Abstracts
      • 2026 Emerging Technology Call for Abstracts
    • CME Claim Form
    • SAGES Past, Present, Future, and Related Meeting Information
    • SAGES Related Meetings & Events Calendar
  • Join SAGES!
    • Membership Application
    • Membership Benefits
    • Membership Types
      • Requirements and Applications for Active Membership in SAGES
      • Requirements and Applications for Affiliate Membership in SAGES
      • Requirements and Applications for Associate Active Membership in SAGES
      • Requirements and Applications for Candidate Membership in SAGES
      • Requirements and Applications for International Membership in SAGES
      • Requirements for Medical Student Membership
    • Member Spotlight
    • Give the Gift of SAGES Membership
  • Patients
    • Join the SAGES Patient Partner Network (PPN)
    • Patient Information Brochures
    • Healthy Sooner – Patient Information for Minimally Invasive Surgery
    • Choosing Wisely – An Initiative of the ABIM Foundation
    • All in the Recovery: Colorectal Cancer Alliance
    • Find A SAGES Surgeon
  • Publications
    • Sustainability in Surgical Practice
    • SAGES Stories Podcast
    • Patient Information Brochures
    • Patient Information From SAGES
    • TAVAC – Technology and Value Assessments
    • Surgical Endoscopy and Other Journal Information
    • SAGES Manuals
    • MesSAGES – The SAGES Newsletter
    • COVID-19 Archive
    • Troubleshooting Guides
  • Education
    • Wellness Resources – You Are Not Alone
    • Avoid Opiates After Surgery
    • SAGES Subscription Catalog
    • SAGES TV: Home of SAGES Surgical Videos
    • The SAGES Safe Cholecystectomy Program
    • Masters Program
    • Resident and Fellow Opportunities
      • MIS Fellows Course
      • SAGES Robotics Residents and Fellows Courses
      • SAGES Free Resident Webinar Series
      • Fluorescence-Guided Surgery Course for Fellows
      • Fellows’ Career Development Course
    • SAGES S.M.A.R.T. Enhanced Recovery Program
    • SAGES @ Cine-Med Products
      • SAGES Top 21 Minimally Invasive Procedures Every Practicing Surgeon Should Know
      • SAGES Pearls Step-by-Step
      • SAGES Flexible Endoscopy 101
    • SAGES OR SAFETY Video Activity
  • Opportunities
    • Fellowship Recognition Opportunities
    • SAGES Advanced Flexible Endoscopy Area of Concentrated Training (ACT) SEAL
    • Multi-Society Foregut Fellowship Certification
    • Research Opportunities
    • FLS
    • FES
    • FUSE
    • Jobs Board
    • SAGES Go Global: Global Affairs and Humanitarian Efforts
  • OWLS/FLS
You are here: Home / Abstracts / Comparative Study of the Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Renal Function and Urine Oxalate Excretion

Comparative Study of the Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Renal Function and Urine Oxalate Excretion

Mingwei Ni, MD, PhD1, John Lieske, MD2, Todd Kellogg, MD2. 1Kaiser Permanente South Baltimore County Medical Center, 2Mayo Clinic

Laparoscopic Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the most commonly performed bariatric procedures. Hyperoxaluria is common after RYGB and is associated with increased incidence of calcium oxalate kidney stones. However, the effect of SG on nephrolithiasis risk is less clear. The potential impact of bariatric surgery on renal function remains unclear. Therefore, we conducted a retrospective study to evaluate changes in urine oxalate excretion and renal function in a cohort of patients in the first year after Roux-en-Y gastric bypass versus sleeve gastrectomy. Patients undergoing RYGB or SG at Mayo Clinic were identified between 2000 and 2013. Pre- and post-operative urinary oxalate levels were available in a total of 18 RYGB and 7 SG patients. Estimated glomerular filtration rate (eGFR) was determined using the CKD EPI creatinine equation. Pre and postoperative serum Creatinine (Cr) data were available for 260 RYGB and 107 SG patients. These patients were further stratified into groups of normal preoperative renal function and chronic renal insufficiency based on eGFR, and the effects of RYGB versus SG on the renal function were further evaluated. By one year after surgery, the %EWL is 69.2±1.3% in RYGB and 59.5±4.9% in SG, respectively. Postoperative urine oxalate excretion was measured at 6 months and 12 months after index surgery. In RYGB patients, it was 0.34±0.16 mmol/L (6 months) and 0.56±0.23 mmol/L (12 months). In SG patients, it was 0.24±0.07 mmol/L (6 months) and 0.28±0.13 mmol/L (12 months). Urine oxalate excretion increased significantly 1 year after RYGB (p<0.01), but did not change after SG. Postoperative Cr decreased significantly 6 months and 12 months after RYGB (p<0.01), but remained unchanged after SG. In terms of postoperative eGFR, there was no significant change in normal renal function patients after either bariatric procedure. However, it increased significantly after lap RYGB (p<0.001) in chronic renal insufficiency patients. The change in eGFR was not observed chronic renal insufficiency patients after SG. Our results suggest urine oxalate excretion increases after RYGB but not SG. In renal insufficient patients, serum Cr falls after RYGB but not SG. Similarly, eGFR increased significantly after RYGB but not SG in these patients. There was no change in either Cr or eGFR in normal renal function patient underwent bariatric surgery. Furthermore, the changes in serum Cr and eGFR were not associated with %EWL after surgery. Longer term follow up will be needed to determine if these effects persist over time.


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 77286

Program Number: P570

Presentation Session: Poster (Non CME)

Presentation Type: Poster

61

Share this:

  • Click to share on X (Opens in new window) X
  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on LinkedIn (Opens in new window) LinkedIn
  • Click to share on Pinterest (Opens in new window) Pinterest
  • Click to share on WhatsApp (Opens in new window) WhatsApp
  • Click to share on Reddit (Opens in new window) Reddit
  • Click to share on Pocket (Opens in new window) Pocket
  • Click to share on Mastodon (Opens in new window) Mastodon
  • Click to share on Threads (Opens in new window) Threads
  • Click to share on Bluesky (Opens in new window) Bluesky

Related


sages_adbutler_leaderboard

Hours & Info

11300 West Olympic Blvd, Suite 600
Los Angeles, CA 90064

1-310-437-0544

[email protected]

Monday – Friday
8am to 5pm Pacific Time

Find Us Around the Web!

  • Bluesky
  • X
  • Instagram
  • Facebook
  • YouTube

Copyright © 2025 · SAGES · All Rights Reserved

Important Links

Healthy Sooner: Patient Information

SAGES Guidelines, Statements, & Standards of Practice

SAGES Manuals