Jonathan Imran, MD, Tarik Madni, MD, Audra Clark, MD, Erica Hodgman, MD, Tjasa Hranjec, MD, Daniel Scott, MD, Sara Hennessy, MD. University Of Texas Southwestern Medical Center
Background: Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for morbid obesity and is becoming increasingly popular in bariatric surgery. The resulting alteration in gastrointestinal anatomy after LSG may lead to changes in nutritional parameters such as serum prealbumin, which if low, is an early indicator of malnutrition. The objective of this study was to assess the relationship between measured serum prealbumin and excess weight loss (EWL%) three months after LSG.
Methods: A retrospective review was performed of all patients who underwent a LSG at a single institution between 07/2014 and 12/2015. Patients with ≤ 30% EWL were compared to patients with > 30% EWL. Patient demographics, comorbidities, perioperative factors and 3 month nutritional assessment were analyzed by univariate analysis using Wilcoxon rank sum, Chi-square, and Fisher’s exact tests where appropriate.
Results: A total of 201 patients underwent LSG of which 160 patients had complete data. At 3 month follow up 56/160 patients (35 %) had > 30 % EWL. Patients with an EWL of > 30 % had a mean (+/-SEM) serum prealbumin level of 18.5 +/- 0.54 mg/dL versus 23.8 +/- 2.81 mg/dL for those with an EWL ≤ 30 %, (p = .004). There was no statistically significant difference between mean (+/-SEM) serum albumin levels at 3 months in patients with > 30 % versus ≤ 30 % EWL (4.19 +/- 0.04 g/dL vs. 4.13 +/- 0.03 g/dL, p = .41).
Conclusion: Patients with > 30 % EWL at 3 month follow up have lower measured serum prealbumin levels compared to patients with ≤ 30 % EWL, despite having normal albumin levels. Long-term follow up is necessary to further identify the relationship between albumin, pre-albumin and EWL in bariatric patients.
Presented at the SAGES 2017 Annual Meeting in Houston, TX.
Abstract ID: 80380
Program Number: P573
Presentation Session: Poster (Non CME)
Presentation Type: Poster