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A Retrospective Analysis of Clinical Outcome of Bariatric Surgery in Morbidly Obese Diabetes Mellitus Patients

Ithiphon Viratanapanu, MD1, Chavalit Romyen, PhD2, Sikarin Sornphiphatphong, MD1, Worawit Kattipatanapong, MD1, Kongpon Tangpanitandee, MD1, Ajjana Techagumpuch, MD3, Krit Kitisin, MD1, Suppa-ut Pungpapong, MD1, Chadin Tharavej, MD1, Patpong Navicharern1, Patchaya Boonchayaanant, MD4, Suthep Udomsawaengsup1. 1Department Of Surgery, Faculty Of Medicine, Chulalongkorn University, 2Faculty Of Pharmaceutical Science, Chulalongkorn University, 3Department Of Surgery, Faculty Of Medicine, Thammasat University, 4Department Of Internal Medicine, Faculty Of Medicine, Chulalongkorn University

Introduction: Bariatric surgery is a choice of treatment in morbidly obese patients with Diabetes Mellitus (DM) type II who has inadequate control diabetes with medical treatment. This study aims to evaluate the clinical outcome of bariatric surgery in morbidly obese DM patients.

Methods and procedures: Retrospective study of morbidly obese patients with DM type II who underwent bariatric surgery in King Chulalongkorn Memorial Hospital from September 2003 to March 2016 was collected. Pre-operative body mass index (BMI), DM type II remission, blood pressure and lipid profile were compared with data at 1 year after surgery as clinical outcome by chi-square and T-test analysis.

Results: A total of 73 patients were included in the analysis. Of all, 43 (58.9%) patients were women and mean (standard deviation, SD) age was 41.8 (12.2) years. At 1 year after bariatric surgery compared with pre-operative, 61 (83.6%) patients had DM remission; mean (SD) BMI was 36.9 (8.9) kg/m2 vs 50.9 (10.9) kg/m2 (p<0.001); mean (SD) diastolic blood pressure (DBP) was 76.7 (13) mmHg vs 82.7 (11.1) mmHg (p=0.019); mean (SD) triglyceride (TG) level was 111.8 (95) mg/dL vs 162 (99.1) mg/dL (p<0.001); and mean (SD) HDL level was 50.8 (11.2) mg/dL vs 43.7 (10.7) mg/dL (p<0.001).  

Conclusions: Bariatric surgery demonstrates BMI, DBP, TG level reduction, and DM remission with increases HDL level significantly at 1 year after surgery. Thus bariatric surgery can be an option for improve quality of life in morbidly obese DM patients. 


Presented at the SAGES 2017 Annual Meeting in Houston, TX.

Abstract ID: 86997

Program Number: P656

Presentation Session: iPoster Session (Non CME)

Presentation Type: Poster

47

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