A Novel Bioresorbable/Biointegratable/Biocompatible Dressing for Negative Pressure Wound Therapy
Samuel Tahk, MD, PhD1, Renford Cindass, MD1, Kevin Wu, MD2, Nicholas Robbins, DO3, Jian Ling, PhD4, Bijaya Parida, PhD2, Vijay Gorantla, MD, PhD5, Erik Weitzel, MD2, Michael Davis, MD2. 1San Antonio Military Medical Center, 259th Medical Wing United States Air Force, 3University of Texas Health Sciences Center, 4Southwest Research Institute at San Antonio, 5University of… Continue Reading
A prospective randomized controlled study comparing ultrasonic dissector with electrocautery for axillary dissection in patients of carcinoma breast
Nikhil Gupta, Dr, Ananya Deori, Dr, Arun K Gupta, Dr, Dipankar Naskar, Dr, C K Durga, Dr. PGIMER Dr RML Hospital, DelhiBackground: The ultrasonic dissector, commonly known as the harmonic scalpel, has been in use for achieving haemostasis in surgery for almost 20 yrs. Its advantages in breast surgery, especially in the dissection of axilla,… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
AN EVALUATION OF NOVEL MEDICAL DEVICES AND OTHER INTERVENTIONS IN THE TREATMENT OF TENSION PNEUMOTHORAX IN A SWINE MODEL
Rowan R Sheldon, MD, Michael J Derickson, MD, Woo S Do, MD, Dominic M Forte, MD, Jessica B Weiss, MD, Matthew J Eckert, Matthew J Martin, MD. Madigan Army Medical Center, Tacoma, WAObjectives: Tension pneumothorax (tPTX) is the second most common cause of preventable death in trauma. Needle decompression is the first-line intervention but has… Continue Reading
EXTENDING THE GOLDEN HOUR FOR ZONE 1 REBOA: IMPROVED SURVIVAL AND REPERFUSION INJURY WITH INTERMITTENT VERSUS CONTINUOUS REBOA IN A PORCINE SEVERE TRUNCAL HEMORRHAGE MODEL
John Kuckelman, Morgan Barron, Donald Moe, Michael Derickson, Cody Phillips, Joseph Kononchik, Michael Lallemand, Shannon Marko, Matthew Eckert, Matthew Martin. Madigan Army Medical CenterINTRODUCTION: Non-compressible truncal hemorrhage can be temporarily controlled using resuscitative endovascular occlusion of the aorta (REBOA). Prolonged ischemia has limited REBOA application, but intermittent inflation schedules may be a strategy to mitigate… Continue Reading
Final Report of a Randomized Phase 1b Trial to Assess Sequencing of the E39 and E39′ Vaccines to Optimize Long-term Antitumor Immunity in Folate Binding Protein (FBP)-Expressing Breast and Ovarian Tumors
John W Myers, MD1, Kaitlin M Peace, MD1, Timothy J Vreeland, MD2, Diane F Hale, MD1, Doreen O Jackson, MD1, Julia M Greene, MD1, Tommy A Brown, MD1, Guy T Clifton, MD1, George E Peoples, MD3, Elizabeth A Mittendorf, MD, PhD2. 1Department of Surgery, Brooke Army Medical Center, Ft. Sam Houston, TX, 2The University of… Continue Reading
INHIBITION OF TLR-4 ATTENUATES SYSTEMIC IMMUNE RESPONSE IN HEMORRHAGIC SHOCK
Samuel W Hoppe, MD, William Chang, MD, Michael Kilbourne, MD, Balakrishna M Prasad, PhD. Dwight D Eisenhower Army Medical CenterOBJECTIVES: Activation of toll-like receptor 4 (TLR-4) by damage associated molecular patterns (DAMPs) has been implicated in the systemic activation of the immune system in hemorrhagic shock. This immune response may be deleterious in some patients. … Continue Reading
MicroRNA-124 Inhibition Upregulates Hippocampal Expression of Genes Central to Synaptic Plasticity, Glucocorticoid Signaling, and Neurogenesis in a Rat Model of Gulf War Illness
Nicole Laferriere, MD, Wendy Kurata, MS, C. T. Grayson, MD, Lisa Pierce, DSc. Tripler Army Medical CenterOBJECTIVES: Gulf War Illness (GWI) is a chronic, multisymptom illness marked by cognitive and mood dysfunction and disrupted neuroendocrine-immune homeostasis affecting 30% of GW veterans. After 25+ years, useful treatments are lacking and its cause is poorly understood, although… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
MicroRNA-17 and the prognosis of human carcinomas: a systematic review and meta-analysis.
Chengzhi Huang, Mengya Yu. Guangdong General Hospital (Guangdong Academy of Medical Science)Keywords: microRNA-17; Cancer; Outcome; Prognosis; Meta-analysis. Background: The recognition of biomarkers to predict the outcome of caner is in need. MicroRNA-17 (miR-17) family has been thoroughly studied and reported to contribute to the progress of human carcinomas. miR-17 is one of the most important… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Plasma Co-Administration Improves Resuscitation with Tranexamic Acid or Prothrombin Complex in a Porcine Hemorrhagic Shock Model
John P Kuckelman, Morgan Barron, MD, Donald Moe, Michael Lallemand, John McClellan, Shannon Marko, Matthew Eckert, Matthew Martin. Madigan Army Medical CenterOBJECTIVE: Traumatic coagulopathy has now been well characterized, but still carries high rates of mortality due to bleeding. A "factor-based" resuscitation strategy using pro-coagulant drugs and factor concentrates in lieu of plasma is being… Continue Reading
Role of Mitochondrial Enzymes in Gastrointestinal system of Mitochondrial Myopathy patients
Muhammad Nadeem1, Julian Ambrus, MD1, Steven Schwaitzberg, MD1, John Butsch, MD2. 1University at Buffalo, 2Buffalo General Medical CenterIntroduction: Mitochondria is a small energy producing structure of a cell. Mitochondrial myopathy (MM) is mixed disorder clinically, which can affect various systems besides skeletal muscle. MM starts with muscle weakness or exercise weakness. MM patients have decreased… Continue Reading
- Type:
- Posters
- Topic:
- Basic Science
Saline Hydro-Flotation is Superior to Bioresorable Membranes in Decreasing Intra-Abdominal Adhesion Formation in a Rat Model
John Kuckelman, Morgan Barron, Kevin Kniery, Jeffrey Kay, Joseph Kononchik, Zachary Hoffer, Vance Sohn. Madigan Army Medical CenterINTRODUCTION: Adhesion formation after laparotomy remains a major cause of post-operative morbidity. Hyaluronate/carboxymethylcellulose membranes (HAC) are costly bioresorbable membranes that represent current anti-adhesion therapy. Alternatively, hydro-flotation using saline theoretically provides a transient barrier during adhesion formation. We sought… Continue Reading
Vasopressin Administration During Fluid Resuscitation Alters Expression of Epigenetic Enzymes of Renal Artery in a Pig Model of Hemorrhagic Shock
Jillian M Piaggione, MD1, Lee-Ann M Murata, MSc2, Catherine F Uyehara, PhD2, Dao H Ho, PhD2. 1Department of General Surgery, Tripler Army Medical Center, 2Department of Clinical Investigation, Tripler Army Medical CenterObjectives. Trauma accounts for ~50% of combat-related deaths. Rapid blood loss from trauma can lead to hemorrhagic shock resulting in organ damage. Renal function… Continue Reading