Sharon Chiu, MD, Daniel W Birch, MD, Xinzhe Shi, Arya M Sharma, MD, Shahzeer Karmali, MD. University of Alberta
Introduction: Sleeve gastrectomy (SG) has increased in popularity as both a definitive and staged procedure for morbid obesity. Respectively, gastroesophageal reflux disease (GERD) is a common comorbid disease in bariatric patients. The effect of SG on GERD has not been well studied, thus the goal of this systematic literature review is to analyze the impact of SG on GERD.
Methods: A systematic literature search was conducted using Medline, EMBASE, the Cochrane Database, Scopus, and the gray literature for the keywords “sleeve gastrectomy,” “gastroesophageal reflux,” and equivalents.
Results: Sixteen articles were retrieved. Two articles analyzed GERD as a primary outcome, whereas fourteen included GERD as a secondary study outcome. Four studies showed an increase in GERD after SG. Seven studies found reduced GERD symptoms post-SG. Four studies included only the post-operative prevalence of GERD. One study did not include data on prevalence of GERD.
Conclusion: The evidence on the impact of SG on GERD does not consolidate to a consensus. The studies show differing outcomes. Hence, dedicated studies that objectively evaluate GERD after SG are needed to more clearly define the effect of SG on GERD in bariatric patients
Keywords: Sleeve gastrectomy, Gastroesophageal reflux disease, Systematic review
Program Number: P020