Colorectal Cancer in Young Adults in Southern Part of Pakistan – Laparoscopic Management and Outcome at Liaquat University Hospital Hyderabad

ArshadHussain Abro, Dr, Abdul Aziz Laghari, Prof. LUMHS PAKISTAN

OBJECTIVE: To evaluate the laparoscopic management and outcome of colorectal cancer in young adults in Southern part of Pakistan presented at Liaquat University Hospital Hyderabad / Jamshoro.

PATIENTS AND METHODS: The descriptive case series study was conducted in department of surgery at Liaquat University Hospital Hyderabad. All the patients with 10-30 years of age of either gender presented with history of abdominal pain and lump, constipation, anorexia and bleeding per rectum, weight loss were included in the study and were further explored for colorectal carcinoma by histopathology. The frequency and percentage was calculated for categorical variables and mean ±SD was calculated for numerical variables. As this was descriptive case series so there was no any statistical test of significance was applied.

RESULTS: During five year study period, total one hundred patients diagnosed as colorectal carcinoma with means age 20.64±3.43 (SD). Of 100, 72 were males and 46 were females while the common causes identified were radiation, low fiber diet and excessive smoking. The most common tumor detected was adenocarcinoma in 80 patients while the squamous cell carcinoma was most common tumor observed in anal canal in 20 patients. The management options applied were laparoscopic anterior resection in 60 patients, laparoscopic abdominal perineal resection in 25 patients and laparoscopic left and right hemicolectomies in 15 patients. Regarding outcome all patients underwent for chemotherapy and radiotherapy, recurrence occurred in 15 patients on follow up visits while the mortality was 10% during follow up.     

CONCLUSION: It has been concluded that colorectal carcinoma is becoming common cancer in young adults; the management options included laparoscopic anterior resection, laparoscopic abdominal perineal rsection and laparoscopic left / right hemicoloectomies.

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